【摘要】：正重癥肌無力(myasthenia gravis,MG)是一種由抗體介導(dǎo)的乙酰膽堿(Ach)受體(AchR)受損和功能性AchR減少的自身免疫性疾病,其臨床特征是骨骼肌無力和易疲勞,活動后癥狀加重,休息或予膽堿酯酶抑制劑治療后可緩解。鑒于其特殊的病理生理,對MG患者的圍術(shù)期麻醉管理應(yīng)謹(jǐn)慎。1 MG的病理生理MG是一種自身免疫性疾病,主要由AchR抗
[Abstract]:Positive myasthenia gravis (myasthenia gravis,MG) is an autoimmune disease with impaired (AchR) of acetylcholine (Ach) receptor and decrease of functional AchR mediated by antibody. Its clinical characteristics are skeletal muscle weakness and fatigue, and the symptoms after exercise are aggravated. Rest or treatment with cholinesterase inhibitors may relieve the disease. In view of its special pathophysiology, perioperative anesthesia management of MG patients should be careful. 1. 1 MG pathophysiological MG is an autoimmune disease, which is mainly resistant by AchR.
【作者單位】： 皖南醫(yī)學(xué)院弋磯山醫(yī)院麻醉與重癥醫(yī)學(xué)科;
【基金】：安徽省衛(wèi)生廳醫(yī)學(xué)科研項目資助(2010C066)
【分類號】：R614

【參考文獻(xiàn)】

相關(guān)期刊論文 前2條

1 呂寶勝;王卓強;王衛(wèi);解恩宇;房芳;張晨;;七氟烷或丙泊酚復(fù)合瑞芬太尼麻醉在重癥肌無力患者胸腺切除術(shù)中的應(yīng)用[J];解放軍醫(yī)學(xué)雜志;2013年07期

2 魯衛(wèi)華;金孝\，

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