采用血栓彈力圖評估不同麻醉方式對膝關節(jié)置換術患者血液凝固動態(tài)變化的影響
[Abstract]:Objective to evaluate the effect of different anesthetic methods on coagulation function of knee arthroplasty patients by thromboelastography, and to provide evidence for clinical selection of better anesthesia methods. Methods 188 patients with single knee arthroplasty who were hospitalized in Xiangya Hospital of Central South University from December 2013 to September 2015 were studied. They were randomly divided into two groups, 94 cases in each group. The control group was anesthetized by general anesthesia, the observation group by nerve block anesthesia, and the venous blood was taken before, during and after operation to determine the thromboelastogram. The indexes included coagulation time (k), thromboplastin production time (r), thrombus maximum (MA), coagulation angle (偽) coagulation synthesis index (CI) and thrombus reduction rate (LY30) within 30 min after the determination of coagulation time. Results compared with those before and during the operation, the rnk of general anesthesia group decreased significantly, the 偽 -malacci and LY30 increased significantly (P0. 003), while the LY30 of nerve block anesthesia group was significantly higher than that of general anesthesia group (P < 0. 003), but that of nerve block group was significantly higher than that of general anesthesia group (P < 0. 003). The difference was statistically significant (P0. 023), the r of the patients with nerve block anesthesia was significantly higher than that of the general anesthesia group (P < 0. 023), and the r of the patients with nerve block anesthesia was significantly lower than that of the general anesthesia group (P < 0. 006), and the difference was statistically significant (P < 0. 006), compared with that of the general anesthesia group. The k value of the observation group also increased, but the difference was not statistically significant (P0.086), the proportion of (DVT) in the control group was 10.6, and the proportion of DVT in the observation group was 0, the difference was statistically significant (P0.030). Conclusion the coagulation function of patients after operation is obviously changed, and general anesthesia has obvious effect of promoting coagulation. Compared with before, nerve block anesthesia can reverse the coagulation effect, and the proportion of patients with DVT is lower. It is worth popularizing and applying in clinic.
【作者單位】: 中南大學湘雅醫(yī)院麻醉科;
【分類號】:R614
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