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注意缺陷多動(dòng)障礙與正常兒童沖突監(jiān)測功能比較研究

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【摘要】:第一部分不同亞型注意缺陷多動(dòng)障礙兒童家庭環(huán)境與行為比較 目的:對注意缺陷多動(dòng)障礙常見亞型的家庭環(huán)境與沖突監(jiān)測功能進(jìn)行比較,尋求ADH行為問題的危險(xiǎn)因素,探討不同亞型認(rèn)知損傷的差異。方法:選擇ADHD注意缺陷型(ADHD-I型)和混合型(ADHD-C型)各39例、正常兒童38名,進(jìn)行Conners父母問卷PSQ、家庭環(huán)境量表FES-CV的評定和空間整合Simon-Stroop任務(wù)的完成。結(jié)果:量表:①PSQ:ADHD-I型和ADHD-C型的品行問題、學(xué)習(xí)問題、沖動(dòng)-多動(dòng)及多動(dòng)指數(shù)與正常組比較,差異有統(tǒng)計(jì)學(xué)意義(P0.05);兩亞型間上述4個(gè)評分差異有統(tǒng)計(jì)學(xué)意義;②FES-CV:ADHD-I型和ADHD-C型的親密度、情感表達(dá)、矛盾性、知識性、娛樂性、控制性與正常組比較,差異有統(tǒng)計(jì)學(xué)意義(P 0.05);兩亞型間矛盾性評分差異有統(tǒng)計(jì)學(xué)意義。行為學(xué):Simon不一致(Siin)和Stroop不一致(Stin)條件,ADHD-I型和ADHD-C型的反應(yīng)正確率(Siin:0.76±0.13,0.69±0.13;Stin:0.82±0.10,0.78±0.08)和反應(yīng)時(shí)(Siin:876.4±97.34ms,,893.8±130.1ms;Stin:864.4±91.82ms,860.2±125.0ms)與正常組(Siin:0.81±0.11,810.4±136.1;Stin:0.87±0.08,797.4±136.1ms)比較,差異有統(tǒng)計(jì)學(xué)意義(P0.05);兩亞型間Siin及Stin的正確率差異有統(tǒng)計(jì)學(xué)意義;Pearson相關(guān)分析:FES-CV某些環(huán)境因素與ADHD兒童的行為特點(diǎn)存在不同程度相關(guān)性。結(jié)論:不良的家庭環(huán)境是ADHD兒童發(fā)生行為問題的危險(xiǎn)因素,且ADHD-C型的家庭、行為問題較ADHD-I型突出。ADHD兩亞型均存在沖突監(jiān)測功能缺損,損傷程度有所不同,ADHD-C型較ADHD-I型重。 第二部分ADHD兒童沖突監(jiān)測功能事件相關(guān)電位與行為學(xué)研究 目的:對注意缺陷多動(dòng)障礙(ADHD)兒童完成干擾任務(wù)的行為學(xué)和事件相關(guān)電位(ERP)進(jìn)行分析,探討ADHD兒童是否存在沖突監(jiān)測功能損傷,尋求ADHD兒童ERP各成分在不同導(dǎo)聯(lián)的變化特點(diǎn)及意義。方法:選擇ADHD兒童112例、正常兒童101名,進(jìn)行空間整合Simon-Stroop任務(wù)的完成。結(jié)果:行為學(xué):Simon不一致(Siin)和Stroop不一致(Stin)條件,ADHD組的反應(yīng)錯(cuò)誤率(Siin:0.27±0.12,Stin:0.19±0.10)和反應(yīng)時(shí)(Siin:890.35±93.15,Stin:858.15±95.63)與正常組(Siin:0.18±0.14,820.40±106.8;Stin:0.15±0.16,816.94±104.7)比較,差異有統(tǒng)計(jì)學(xué)意義(P0.05);事件相關(guān)電位(ERP):N1和P2成分:波幅和潛伏期在Fz、Fcz、Cz導(dǎo)聯(lián)上與正常組比較,差異有統(tǒng)計(jì)學(xué)意義,但不存在條件主效應(yīng);N2a和N2b成分:波幅和潛伏期在Fz、Fcz導(dǎo)聯(lián)上與正常組比較,差異有統(tǒng)計(jì)學(xué)意義,同時(shí)存在條件主效應(yīng);P3成分:波幅和潛伏期在Cz、Pz導(dǎo)聯(lián)上與正常組比較,差異有統(tǒng)計(jì)學(xué)意義,同時(shí)存在條件主效應(yīng)。結(jié)論:ADHD兒童存在沖突監(jiān)測功能損傷,且整個(gè)認(rèn)知加工過程中,ERP不僅早期成份存在異常,且晚期成分也有異常。ERP各成分所代表的意義有所不同,不同導(dǎo)聯(lián)ERP主成分的變化特點(diǎn)也不同。在Fz、Fcz導(dǎo)聯(lián)上,N1、N2成分變化最為明顯,N2代表沖突監(jiān)測功能的指標(biāo);Cz導(dǎo)聯(lián)是觀察P2成分差異的最好區(qū)域,N1、P2與視覺注意力,忽略無關(guān)信息能力有關(guān);而P3成分則主要在Pz導(dǎo)聯(lián)上呈現(xiàn),是衡量ADHD兒童認(rèn)知功能的客觀指標(biāo)之一。
[Abstract]:Comparison of family environment and behavior of children with attention deficit hyperactivity disorder in different subtypes of the first part Objective: To compare the family environment and the conflict monitoring function of the common subtype of attention deficit hyperactivity disorder, and to find the risk factors of ADH behavior and to explore the difference of the cognitive impairment of different subtypes. Methods:39 cases of ADHD-type (ADHD-I) and mixed type (ADHD-C) and 38 normal children were selected. The evaluation of the family environment scale FES-CV and the completion of the Simon-Stroop were completed. The results were as follows: Q: ADHD-I and ADHD-C. The difference was significant (P0.05). The difference of four scores between the two subcategories was of statistical significance (P <0.05); the difference of the four scores between the two subcategories was of statistical significance; the AFIES-CV: ADHD-I and ADHD-C were close to each other. The difference in degree, emotion expression, contradiction, knowledge, entertainment and control was statistically significant (P 0.05). There was a statistical difference in the difference between the two subcategories. Presense. Behavior: Simon's Inconsistent (Siin) and Stroop Inconsistent (Stin) conditions, ADHD-I and ADHD-C type of reaction accuracy (Siin: 0.76-0.13, 0.69-0.13; Stin: 0.82-0.10, 0.78-0.08) and reaction (Siin: 876.4-97.34 ms, 893.8-130.1 ms; Stin: 864.4-91.82 ms, 860.2-125.0 ms) and normal group (Siin: 0.81-0.11, 810.4-136.1; Sti N: 0.87 (0.08, 797.4, 136.1 ms), the difference was statistically significant (P0.05); the difference of the accuracy of the two subtypes of Siin and Stin was of statistical significance; Pearson correlation analysis: some of the environmental factors of the FES-CV were related to the behavior characteristics of the ADHD children. Sex. Conclusion: The poor family environment is the risk factor of the behavior of ADHD children, and the ADHD-C family and behavior problems are higher than that of the ADHD-I type. The two subtypes of ADHD have the function of conflict monitoring, the degree of damage is different, and the ADHD-C type is higher than that of the ADHD-I type. The second part of the ADHD children's conflict monitoring function event-related potential and line Objective: To study the behavior and event-related potential (ERP) of children with attention deficit hyperactivity disorder (ADHD). Measure the function damage and seek the change of each component of the ADHD children's ERP in different leads Methods:112 children with ADHD were selected,101 normal children, and Simon-Stroop in space. Results: The behavior of Simin and Stroop did not agree (Stin). The reaction error rate of ADHD group (Siin: 0.27-0.12, Stin: 0.19-0.10) and reaction time (Siin: 890.35-93.15, Stin: 858.15-95.63) and normal group (Siin: 0.18-0.14, 820.40-106.8; Stin: 0.15-0.16, 816.94-104) (7) The difference was significant (P0.05); the event-related potential (ERP): N1 and P2: the amplitude and the latency were compared with the normal group in Fz, Fcz and Cz, but there was no conditional main effect; the components of N2a and N2b: amplitude and latent period Compared with the normal group in Fz and Fcz, there was a significant difference in the Fz and Fcz. The main effect of the condition was that the amplitude and the latent period were compared with the normal group in Cz and Pz, and the difference was of statistical significance. Conclusion: In the whole cognitive process, the early component of ADHD is not only abnormal but also in the late stage. There is also an exception. The meaning of the representative of the ERP components is different, and the change of the principal component of the different lead ERP The characteristic is also different. In Fz, Fcz guide, the change of the component of N1 and N2 is the most obvious, and the N2 represents the index of the conflict monitoring function; the Cz lead is the best area for observing the difference of the P2 component, N1, P2 is related to the visual attention, and the independent information ability is ignored; and the P3 component is mainly in Pz. The presentation on the guide is a measure of the cognitive function of the ADHD children.
【學(xué)位授予單位】:蘇州大學(xué)
【學(xué)位級別】:碩士
【學(xué)位授予年份】:2012
【分類號】:R749.94

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