本文選題：網(wǎng)絡(luò)游戲成癮　切入點(diǎn)：動(dòng)脈自旋標(biāo)記灌注成像　出處：《中國(guó)醫(yī)學(xué)計(jì)算機(jī)成像雜志》2015年01期

【摘要】：目的:運(yùn)用動(dòng)脈自旋標(biāo)記成像對(duì)青少年網(wǎng)絡(luò)游戲癮(IGA)患者的腦血流量(CBF)改變進(jìn)行研究。方法:18名IGA及17名健康被試進(jìn)行MRI掃描,進(jìn)行基于體素的兩組CBF比較。運(yùn)用陳氏網(wǎng)絡(luò)成癮量表評(píng)分(CIAS)與18名IGA被試的全腦各區(qū)域的CBF值進(jìn)行相關(guān)分析。結(jié)果:IGA組右側(cè)顳上回、右側(cè)額眶回、右側(cè)豆?fàn)詈�、左�?cè)扣帶回、左側(cè)豆?fàn)詈?海馬旁回、左側(cè)顳中回、左側(cè)中央前回、腦干左側(cè)和左側(cè)直回較對(duì)照組CBF明顯增高;右側(cè)顳上回CBF值與CI AS評(píng)分負(fù)相關(guān)。結(jié)論:本研究通過(guò)ASL技術(shù)無(wú)創(chuàng)地對(duì)IGA被試腦灌注改變進(jìn)行了定量分析,實(shí)驗(yàn)結(jié)果驗(yàn)證了IGA作為一種行為成癮,與物質(zhì)成癮可能具有相似的神經(jīng)生物學(xué)機(jī)制的假說(shuō)。
[Abstract]:Aim: to study the changes of cerebral blood flow (CBF) in patients with internet game addiction (IGA) by arterial spin labeling imaging.Methods MRI scans were performed in 18 IGA subjects and 17 healthy subjects. CBF was compared between the two groups based on voxel.Using Chen's Internet Addiction scale (iad) score, the correlation analysis was made between the CBF values of 18 subjects with IGA in all regions of the brain.Results CBF in the right superior temporal gyrus, right frontal orbital gyrus, right lentiform nucleus, left cingulate gyrus, left lentiform nucleus / pariprahippocampal gyrus, left middle temporal gyrus, left central pregyrus, left left and left straight gyrus of brain stem were significantly higher than those in the control group.The CBF of right superior temporal gyrus was negatively correlated with CI as score.Conclusion: the brain perfusion changes of IGA subjects were quantitatively analyzed by ASL technique, and the results confirmed the hypothesis that IGA, as a behavioral addiction, may have similar neurobiological mechanism with substance addiction.
【作者單位】： 上海交通大學(xué)醫(yī)學(xué)院附屬仁濟(jì)醫(yī)院放射科;上海交通大學(xué)醫(yī)學(xué)院附屬上海精神衛(wèi)生中心青少年心理健康中心;
【基金】：國(guó)家自然科學(xué)基金No.81171325;國(guó)家自然科學(xué)基金No.81201172 上海市科委醫(yī)學(xué)引導(dǎo)項(xiàng)目No.114119a0900~~
【分類號(hào)】：R445.2;R749.99
，

本文編號(hào)：1704613