【摘要】：目的探討早期腦鈉肽(BNP)、C反應蛋白(CRP)、乳酸(Las)水平聯合檢查評估老年感染性休克患者預后的臨床價值。方法回顧性分析2012年6月至2015年3月該院重癥監(jiān)護室(ICU)治療的75例老年感染性休克患者的臨床資料,依據28 d后的存活情況分為存活組(41例)和死亡組(34例),分析不同組別BNP、CRP、Las的差異,并采用受試者工作曲線(ROC)進一步分析。結果死亡組BNP、CRP、Las水平均高于生存組(P0.05);約登指數(Youden)最大原則確定BNP、CRP、Las評估最佳臨界值為:13 310.47 pg/ml、23 mg/L、3.1 mmol/L,此時評估"死亡"的靈敏度、特異度、準確率分別為:82.35%、78.05%、80.00%;67.64%、70.73%、69.33%;79.41%、87.80%、84.00%。三種指標聯合評估時,≥1種、≥2種、3種高于臨界值的靈敏度、特異度、準確率分別為:97.06%、43.90%、68.00%;88.24%、85.37%、86.67%;58.82%、95.12%、78.67%。結論早期聯合檢測BNP、CRP、Las有助于評估老年感染性休克患者預后,這3種中任意≥2種高于臨界值時多提示預后不佳。
[Abstract]:Objective to evaluate the clinical value of early brain natriuretic peptide (BNP) (BNP) C-reactive protein (CRP),) lactate (Las) level in evaluating the prognosis of elderly patients with septic shock. Methods the clinical data of 75 elderly patients with septic shock treated by (ICU) from June 2012 to March 2015 were retrospectively analyzed. According to the survival condition after 28 days, the patients were divided into survival group (41 cases) and death group (34 cases). Results the level of BNP-CRP Las in death group was higher than that in survival group (P0.05), and the critical value of BNP-CRP Las was 13 310.47 mg / ml ~ (23 mg / L) / L ~ 3.1 mmol 路L ~ (-1). The sensitivity, specificity and accuracy of "death" were evaluated as follows: the sensitivity, specificity and accuracy of "death" were 87.3578.05 / 80.0077.6470.730.79.3379.41and 87.804.00 respectively. The sensitivity, specificity, and accuracy of 鈮，

本文編號：2146990