發(fā)布時間：2018-03-13 15:46

  本文選題：重型顱腦損傷　切入點：磁共振波譜　出處：《南昌大學》2017年碩士論文　論文類型：學位論文

【摘要】：目的:通過對重型顱腦損傷患者傷后進行MRI及MRS檢查,并將檢查結果與患者的預后結果之間的關系進行統(tǒng)計學分析,探索MRI與MRS對重型顱腦損傷預后判斷的臨床意義。方法:選取2010年1月到2014年5月在我院接受CT檢查及綜合治療的27例急性重型顱腦損傷患者,入院7d內(nèi)進行頭顱MRI及MRS檢查,采用核磁共振掃描儀及超導磁共振進行T1、T2、Flair序列掃描,選擇合適的靶點進行MRS檢查,明確顱腦損傷的部位及性質(zhì)。對頭顱CT、MRI及MRS的彌漫性軸索損傷影像學圖片及資料進行比照,并且對比頭顱CT與MRI+MRS對彌漫性軸索損傷其中包括原發(fā)性腦干損傷的檢出率,并分析MRS檢出損傷部位及檢出指標與預后的關系。結果:在對重型顱腦損傷中彌漫性軸突損傷包括原發(fā)性腦干損傷的檢出率方面,頭部MRI+MRS檢查的檢出率明顯高于頭部CT檢查(P0.05);6個月后預后評分,GOS4~5分患者的NAA/Cr、NAA/Cho、Cho/Cr比值與1~3分患者的差異顯著(P0.05);Barthal評分60分患者的NAA/Cr、NAA/Cho、Cho/Cr比值與60~41分和≤40分患者的差異顯著(P0.05);重型顱腦損傷病人的損傷位置不同,其預后具有顯著差異(P0.05)。結論:MRI+MRS檢查能夠提高重型顱腦損傷病變的檢出率,早期進行MRI和MRS檢查有利于評估預后。
[Abstract]:Objective: to analyze the relationship between the results of MRI and MRS and the prognosis of patients with severe craniocerebral injury. To explore the clinical significance of MRI and MRS in judging the prognosis of severe craniocerebral injury methods: 27 patients with acute severe craniocerebral injury who received CT examination and comprehensive treatment from January 2010 to May 2014 were examined with MRI and MRS within 7 days after admission. The T _ 1T _ 2T _ 2 flair sequence was scanned by MRI scanner and superconducting magnetic resonance imaging. The location and nature of craniocerebral injury were determined by MRS, and the imaging images and data of diffuse axonal injury of head CT and MRS were compared. The detection rate of diffuse axonal injury, including primary brainstem injury, was compared between CT and MRI MRS. Results: the detection rate of diffuse axonal injury including primary brainstem injury in severe craniocerebral injury was analyzed. The positive rate of head MRI MRS examination was significantly higher than that of head CT scan (P 0.05), and the difference of NAA / Cr ratio between NAA / Cr / NAA / NAA / Choo / Cr ratio and 1 ~ 3 score in patients with prognostic score of 4 ~ 5 months after 6 months was significantly higher than that in patients with 60 points of NAA / Cr / NAA / NAA / Choo / Cr ratio of 60 ~ 41 points and 鈮，

本文編號：1607050