【摘要】：目的探討肺隱球菌病的臨床病理特征、診斷及鑒別診斷。方法收集安徽省胸科醫(yī)院37例確診為肺隱球菌病組織標(biāo)本,對(duì)其臨床病理特征、HE及特殊染色等進(jìn)行回顧性分析,并復(fù)習(xí)相關(guān)文獻(xiàn)。結(jié)果37例肺隱球菌病中男性20例,女性17例,年齡12~80歲,中位年齡45歲。常見(jiàn)臨床癥狀有咳嗽、咳痰、胸痛,部分重癥患者有慢性病或激素治療史,另有15例患者無(wú)癥狀。常見(jiàn)胸部影像學(xué)表現(xiàn)有結(jié)節(jié)影18例,團(tuán)塊狀、片狀影19例,混合病變10例。4例行乳膠凝集試驗(yàn)檢測(cè)均陽(yáng)性,37例行六胺銀染色均陽(yáng)性。結(jié)論肺隱球菌病好發(fā)于青壯年,多數(shù)患者無(wú)免疫功能受損;臨床及影像學(xué)表現(xiàn)無(wú)特異性;多數(shù)病例通過(guò)組織病理學(xué)確診,六胺銀等特殊染色有助于病理診斷;乳膠凝集試驗(yàn)可作為肺隱球菌病的首選輔助診斷手段。
[Abstract]:Objective to investigate the clinicopathological features, diagnosis and differential diagnosis of Cryptococcus pneumoniae. Methods 37 cases of pulmonary Cryptococcosis diagnosed in Anhui chest Hospital were collected and their clinicopathological features, HE and special staining were analyzed retrospectively. the related literatures were reviewed. Results among 37 cases of pulmonary Cryptococcosis, there were 20 males and 17 females, aged 12 鈮，

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