【摘要】：目的探討重度子癇前期(SPE)孕婦及胎兒的動(dòng)脈血流變化情況及硫酸鎂對(duì)其的影響。方法選擇2013年1月至2015年1月該院收治的SPE孕婦174例作為觀察組,正常孕婦174例作為對(duì)照組,觀察組孕婦給予硫酸鎂治療2d,觀察硫酸鎂治療前后孕婦大腦中動(dòng)脈、子宮動(dòng)脈、子宮螺旋動(dòng)脈、臍動(dòng)脈、胎兒大腦中動(dòng)脈血流及孕婦血壓、頭暈眼花癥狀、無(wú)負(fù)荷試驗(yàn)(NST)的變化。結(jié)果觀察組治療前、后與對(duì)照組孕婦和胎兒大腦中動(dòng)脈阻力指數(shù)(RI)值、搏動(dòng)指數(shù)(PI)值、收縮期峰值流速/舒張末期流速(S/D)值比較,差異均無(wú)統(tǒng)計(jì)學(xué)意義(P0.05)。觀察組治療前子宮動(dòng)脈和子宮螺旋動(dòng)脈RI值、PI值、S/D值明顯高于對(duì)照組(P0.05);治療后子宮動(dòng)脈RI值、PI值、S/D值明顯低于治療前(P0.05)。觀察組治療前臍動(dòng)脈RI值、PI值、S/D值均高于對(duì)照組(P0.05);治療后臍動(dòng)脈PI值、S/D值較治療前降低,但差異無(wú)統(tǒng)計(jì)學(xué)意義(P0.05)。治療后,觀察組收縮壓、舒張壓、平均動(dòng)脈壓與治療前比較均有所降低,頭暈眼花比例較治療前降低,但差異均無(wú)統(tǒng)計(jì)學(xué)意義(P0.05),而NST無(wú)反應(yīng)的發(fā)生率均明顯低于治療前(P0.05)。結(jié)論硫酸鎂治療能夠明顯改善SPE患者子宮動(dòng)脈、子宮螺旋動(dòng)脈的血流情況,能夠改善胎兒宮內(nèi)儲(chǔ)備情況。
[Abstract]:Objective to investigate the changes of arterial blood flow in pregnant women and fetuses with severe preeclampsia (SPE) and the effect of magnesium sulfate on it. Methods from January 2013 to January 2015, 174 pregnant women with SPE were selected as the observation group and 174 normal pregnant women as the control group. The pregnant women in the observation group were treated with magnesium sulfate for 2 days. The changes of middle cerebral artery, uterine spiral artery, umbilical artery, fetal middle cerebral artery blood flow, maternal blood pressure, dizziness and (NST) were observed before and after magnesium sulfate treatment. Results before and after treatment, there was no significant difference in middle cerebral artery resistance index (RI), pulsatility index (PI) and systolic peak velocity / end diastolic velocity (S 鈮，

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