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DSA介導(dǎo)下輸卵管近端梗阻介入再通術(shù)聯(lián)合IUI治療不孕癥的臨床研究

發(fā)布時(shí)間:2019-04-22 10:40
【摘要】:目的:探討數(shù)字減影血管造影機(jī)(DSA)介導(dǎo)下輸卵管近端梗阻介入再通術(shù)聯(lián)合夫精宮腔內(nèi)人工授精(IUI)的臨床效果。方法:2010年1月至2012年12月輸卵管近端梗阻介入再通術(shù)成功后接受IUI治療的191例不孕患者為觀察組,取同期無輸卵管近端梗阻行IUI的746例患者為對(duì)照組,對(duì)兩組的臨床資料進(jìn)行分析。結(jié)果:觀察組臨床妊娠率(30.37%)與對(duì)照組(27.75%)相比較,差異無統(tǒng)計(jì)學(xué)意義(P0.05);各不同IUI原因組內(nèi)觀察組臨床妊娠率與對(duì)照組相比較,差異均無統(tǒng)計(jì)學(xué)意義(P0.05)。在觀察組中,4個(gè)IUI原因組間臨床妊娠率相比較,差異有統(tǒng)計(jì)學(xué)意義(P0.05);行組間卡方分割后,男性因素及宮頸因素組臨床妊娠率高于其他兩組(P0.01)。在對(duì)照組中,4個(gè)IUI原因組間臨床妊娠率相比較,差異有統(tǒng)計(jì)學(xué)意義(P0.01);行組間卡方分割后,男性因素組及宮頸因素組臨床妊娠率高于其他兩組(P0.01)。結(jié)論:DSA介導(dǎo)下輸卵管近端梗阻介入再通術(shù)聯(lián)合IUI的臨床效果良好,不同IUI原因中男性因素及宮頸因素患者的臨床妊娠率高于其他因素的患者。
[Abstract]:Aim: to investigate the clinical effect of interventional recanalization of proximal tubal obstruction mediated by digital subtraction angiography (DSA) combined with artificial insemination (IUI). Methods: from January 2010 to December 2012, a total of 191 infertile patients who received IUI after successful interventional recanalization of proximal fallopian tube obstruction were selected as the observation group, and 746 patients without obstruction of the proximal fallopian tube during the same period were selected as the control group. The clinical data of the two groups were analyzed. Results: the clinical pregnancy rate in the observation group (30.37%) was not significantly different from that in the control group (27.75%) (P0.05). There was no significant difference in the clinical pregnancy rate between the observation group and the control group in the different IUI reasons group (P0.05). In the observation group, the clinical pregnancy rate of the four IUI causes group was significantly higher than that of the other two groups (P0.05), and the clinical pregnancy rate of the male factor and cervical factor group was higher than that of the other two groups (P0.01). In the control group, there was a significant difference in the clinical pregnancy rates among the four IUI causes groups (P0.01), and the clinical pregnancy rates in the male factor group and cervical factor group were higher than those in the other two groups (P0.01). Conclusion: DSA-mediated interventional recanalization of proximal fallopian tube obstruction combined with IUI has a good clinical effect. The clinical pregnancy rate of male and cervical factors in different IUI causes is higher than that of other factors.
【作者單位】: 汕頭大學(xué)醫(yī)學(xué)院第一附屬醫(yī)院;廣州醫(yī)科大學(xué)附屬第三醫(yī)院;
【分類號(hào)】:R711.6

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