子宮內(nèi)膜癌高危因素對(duì)淋巴結(jié)切除臨床決策的指導(dǎo)意義
發(fā)布時(shí)間:2018-12-16 22:56
【摘要】:目的Ⅰ期子宮內(nèi)膜癌手術(shù)范圍是否應(yīng)常規(guī)包括淋巴結(jié)切除國內(nèi)外專家意見尚未統(tǒng)一。本研對(duì)臨床Ⅰ期子宮內(nèi)膜癌高危因素手術(shù)前后的診斷符合率進(jìn)行分析,探討臨床Ⅰ期子宮內(nèi)膜癌行淋巴結(jié)切除的指征。方法回顧性分析2010-05-10-2013-05-10青島市立醫(yī)院收治的127例Ⅰ期子宮內(nèi)膜癌患者臨床資料,所有患者均行腹腔鏡下筋膜外全子宮+雙附件切除+盆腔淋巴結(jié)清除術(shù)(其中55例同時(shí)行腹主動(dòng)脈旁淋巴結(jié)清除術(shù))。比較手術(shù)前后組織學(xué)分級(jí)、病理類型、肌層浸潤深度和淋巴結(jié)轉(zhuǎn)移的診斷符合情況,分析其與淋巴結(jié)轉(zhuǎn)移的相關(guān)性。結(jié)果手術(shù)前后組織學(xué)分級(jí)診斷符合率為76.4%(97/127),8.1%(9/111)的患者新增為高危因素合并者;病理類型診斷符合率為89.8%(114/127),10.2%(13/127)的患者新增為高危因素合并者;肌層浸潤診斷符合率為74.8%(95/127),20.4%(20/98)的患者新增為高危因素合并者;淋巴轉(zhuǎn)移診斷符合率為89.0%(113/127),11.0%(14/127)的患者新增為高危因素合并者。14例淋巴結(jié)有轉(zhuǎn)移,其中盆腔淋巴結(jié)轉(zhuǎn)移10例,腹主動(dòng)脈旁淋巴結(jié)轉(zhuǎn)移1例,盆腔及腹主動(dòng)脈旁淋巴結(jié)共同轉(zhuǎn)移3例。2例術(shù)后病理確診侵犯宮頸間質(zhì),其中1例伴有盆腔淋巴結(jié)轉(zhuǎn)移。11.8%(15/127)的患者術(shù)后手術(shù)病理分期升高。淋巴結(jié)轉(zhuǎn)移與組織學(xué)分級(jí)相關(guān),χ~2=8.444,P=0.015;與肌層浸潤相關(guān),χ~2=7.601,P=0.004;而與病理類型無關(guān),χ~2=0.995,P=0.156。病理確診的低;颊(中、高分化子宮內(nèi)膜樣腺癌且肌層浸潤1/2)淋巴結(jié)轉(zhuǎn)移率為2.7%(2/75)。結(jié)論子宮內(nèi)膜癌高危因素術(shù)前判斷準(zhǔn)確性不高,低;颊咭部砂l(fā)生淋巴結(jié)轉(zhuǎn)移,因此主張對(duì)臨床Ⅰ期子宮內(nèi)膜癌患者行全面的分期手術(shù),更好地指導(dǎo)術(shù)后輔助治療方案選擇,從而改善患者預(yù)后。
[Abstract]:Objective whether the operative scope of stage I endometrial carcinoma should include lymphadenectomy is not uniform at home and abroad. This study analyzed the diagnostic coincidence rate before and after surgery for clinical stage I endometrial carcinoma, and discussed the indications of lymph node resection for clinical stage 鈪,
本文編號(hào):2383184
[Abstract]:Objective whether the operative scope of stage I endometrial carcinoma should include lymphadenectomy is not uniform at home and abroad. This study analyzed the diagnostic coincidence rate before and after surgery for clinical stage I endometrial carcinoma, and discussed the indications of lymph node resection for clinical stage 鈪,
本文編號(hào):2383184
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