【摘要】：探討淋巴脈管間隙浸潤對早期宮頸癌預后的影響。查閱淋巴脈管間隙浸潤(lymphovascular space invasion,LVSI)與早期宮頸癌相關文獻,文獻涉及早期宮頸癌保守性手術、根治術后長期隨訪觀察LVSI與預后的影響�；顧z標本與根治術標本比較,分析其對淋巴轉移、浸潤深度的預測價值。共計34篇文獻符合要求,部分文獻顯示淋巴脈管間隙浸潤不是宮頸癌預后的獨立危險因素,否定其作為早期宮頸癌保留生育功能的評價指標,而部分文獻顯示LVSI與預后相關。臨床觀察發(fā)現(xiàn)LVSI陽性患者保守性手術治療仍應謹慎。淋巴脈管間隙浸潤作為早期宮頸癌保留生育功能的評價指標尚存爭議,其可能與淋巴轉移有關,后者是宮頸癌不良預后的獨立危險因素。
[Abstract]:To investigate the effect of lymphatic vascular space infiltration on early prognosis of cervical cancer. The literature related to early cervix cancer and lymphatic vascular interstitial infiltration (lymphovascular space invasion,LVSI) was reviewed. The literature involved conservative surgery for early cervical cancer. The long-term follow-up after radical resection was to observe the influence of LVSI on prognosis. The predictive value of biopsy specimen and radical operation specimen in lymphatic metastasis and depth of invasion was analyzed. A total of 34 articles met the requirements. Some literatures showed that lymphatic vascular space infiltration was not an independent risk factor for the prognosis of cervical cancer. It was denied that it was an index to evaluate the reproductive function of early cervical cancer, while some literatures showed that LVSI was related to prognosis. Clinical observation showed that conservative surgical treatment of LVSI positive patients should be cautious. Lymphatic vascular interstitial infiltration, which is an independent risk factor for the poor prognosis of cervical cancer, remains controversial as an index to evaluate the reproductive function of early cervical cancer, and it may be related to lymphatic metastasis.
【作者單位】： 北京市通州區(qū)婦幼保健院婦產(chǎn)科;首都醫(yī)科大學附屬北京朝陽醫(yī)院婦產(chǎn)科;
【基金】：北京市自然科學基金(7122069) 北京市科學技術委員會科技計劃(Z131100004013018) 北京市金橋工程種子資金項目(2014-2016)~~
【分類號】：R737.33

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相關期刊論文 前4條

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本文編號：2242772