婦科腫瘤患者輸尿管支架相關(guān)性尿路感染的病原學(xué)分析及耐藥性研究
本文選題:婦科腫瘤 + 尿路感染; 參考:《中國(guó)消毒學(xué)雜志》2017年05期
【摘要】:目的探討婦科腫瘤患者留置輸尿管支架并發(fā)醫(yī)院尿路感染情況。方法回顧性分析浙江省腫瘤醫(yī)院2010年1月-2015年6月留置輸尿管支架的婦科腫瘤患者尿路感染情況。結(jié)果 174例患者中出現(xiàn)尿路感染127例(72.9%),共分離出112株病原菌,其中革蘭陰性菌75株(67%),以大腸埃希菌和肺炎克雷伯菌為主;革蘭陽(yáng)性菌35株(31.3%),以糞腸球菌、金黃色葡萄球菌為主;真菌2株(1.8%),均為白色假絲酵母菌。大腸埃希菌對(duì)頭孢曲松、氨芐西林/舒巴坦、慶大霉素耐藥率較高(57.5%~70.3%);肺炎克雷伯菌對(duì)呋喃妥因耐藥率較高為50%;糞腸球菌對(duì)紅霉素、慶大霉素、氯潔霉素耐藥率較高(61.9%~100%);金黃色葡萄球菌對(duì)青霉素G、紅霉素、氯潔霉素耐藥率較高(50%~75%)。結(jié)論留置輸尿管支架的婦科腫瘤患者尿路感染率較高,臨床應(yīng)加強(qiáng)感染患者的細(xì)菌學(xué)監(jiān)測(cè),根據(jù)病原學(xué)及藥敏結(jié)果合理選擇抗菌藥物,減少耐藥株的產(chǎn)生,提高醫(yī)院感染的治愈率。
[Abstract]:Objective to investigate the nosocomial urinary tract infection in patients with gynecological tumor.Methods the urinary tract infection of gynecological tumor patients with ureteral stents in Zhejiang Cancer Hospital from January 2010 to June 2015 was analyzed retrospectively.Results among 174 patients, 127 patients had urinary tract infection and 112 pathogenic bacteria were isolated, of which 75 were Gram-negative bacteria, mainly Escherichia coli and Klebsiella pneumoniae, 35 Gram-positive strains were Enterococcus faecalis and Staphylococcus aureus.The two fungi were Candida albicans.Escherichia coli showed higher resistance to ceftriaxone, ampicillin / sulbactam, gentamicin, and gentamicin. The resistance rate of Klebsiella pneumoniae to furantoin was 50, and Enterococcus faecalis to erythromycin and gentamicin.The resistance rate of Chloromycin to penicillin G, erythromycin and chloromycin was higher than that of Staphylococcus aureus to penicillin G, erythromycin and chlorchilamycin, and the resistance rate of Staphylococcus aureus to penicillin G, erythromycin and chlortetracycline was higher.Conclusion the urinary tract infection rate of gynecological tumor patients with ureteral stents is higher. The bacteriological monitoring of infected patients should be strengthened and antibiotics should be reasonably selected according to the results of etiology and drug sensitivity in order to reduce the occurrence of drug resistant strains.To improve the cure rate of nosocomial infection.
【作者單位】: 浙江省腫瘤醫(yī)院;
【分類號(hào)】:R691.3;R737.3
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