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女性盆腔漿液性癌20例臨床病理分析

發(fā)布時間:2018-04-14 13:09

  本文選題:盆腔腫瘤 + 漿液性癌; 參考:《臨床與實驗病理學(xué)雜志》2015年03期


【摘要】:目的探討女性盆腔漿液性癌(pelvic serous carcinoma,PSC)的臨床病理學(xué)特征、免疫表型、發(fā)病機制及鑒別診斷。方法回顧性分析20例PSC的臨床病理資料、組織學(xué)形態(tài)及免疫表型,并復(fù)習(xí)相關(guān)文獻。結(jié)果 20例PSC,年齡23~87歲,平均58.9歲。PSC可發(fā)生于輸卵管、卵巢和腹膜,常因腹脹、腹痛或盆腔占位就診,發(fā)現(xiàn)時常廣泛累及盆腔多個臟器,不易明確原發(fā)部位。輸卵管漿液性癌原發(fā)灶小,易種植,卵巢和腹膜漿液性癌常伴有漿液性輸卵管上皮內(nèi)癌(serous tubal intraepithelial carcinoma,STIC)。結(jié)論輸卵管黏膜上皮細胞可能是PSC的主要來源。診斷PSC時需仔細檢查輸卵管以明確其原發(fā)部位,病變廣泛累及腹膜時需與腹膜間皮瘤和盆腔外腺癌腹膜轉(zhuǎn)移相鑒別。
[Abstract]:Objective to investigate the clinicopathological features, immunophenotype, pathogenesis and differential diagnosis of female pelvic serous carcinoma (serous).Methods the clinicopathological data, histological morphology and immunophenotype of 20 cases of PSC were analyzed retrospectively.Results 20 cases of PSC-23 ~ 87 years old, mean 58.9 years old. PSC can occur in oviduct, ovary and peritoneum, often due to abdominal distension, abdominal pain or pelvic space occupying. It is often found that multiple organs of pelvic cavity are frequently involved and it is difficult to identify the primary location.Serous carcinoma of fallopian tube is small and easy to implant. Ovarian and peritoneal serous carcinoma is often accompanied by serous tubal intraepithelial carcinoma.Conclusion the epithelial cells of fallopian tube mucosa may be the main source of PSC.In the diagnosis of PSC, the fallopian tubes should be carefully examined to identify the primary location, and peritoneal metastases should be distinguished from peritoneal mesothelioma and extrapelvic adenocarcinoma when the lesions are extensively involved in the peritoneum.
【作者單位】: 首都醫(yī)科大學(xué)石景山教學(xué)醫(yī)院/北京市石景山醫(yī)院病理科;
【分類號】:R737.3

【相似文獻】

相關(guān)期刊論文 前10條

1 王波,張貴宇;卵巢外腹膜乳頭狀漿液性癌[J];國外醫(yī)學(xué).婦產(chǎn)科學(xué)分冊;1995年02期

2 王蘇榮,王波,李曉明;卵巢微乳頭型漿液性癌的研究進展[J];中華婦產(chǎn)科雜志;2005年08期

3 孫e,

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