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早期子宮內(nèi)膜癌淋巴結(jié)切除術(shù)的臨床價(jià)值分析

發(fā)布時(shí)間:2018-03-14 16:38

  本文選題:早期子宮內(nèi)膜癌 切入點(diǎn):腹膜后淋巴結(jié)切除 出處:《上海交通大學(xué)》2014年碩士論文 論文類型:學(xué)位論文


【摘要】:子宮內(nèi)膜癌是最常見的婦科腫瘤之一,淋巴結(jié)轉(zhuǎn)移是其最主要的轉(zhuǎn)移途徑。自1988年起,F(xiàn)IGO分期由臨床分期轉(zhuǎn)為手術(shù)-病理分期。標(biāo)準(zhǔn)的手術(shù)分期包括盆腔淋巴結(jié)和腹主動(dòng)脈淋巴結(jié)切除,然而對(duì)于早期子宮內(nèi)膜癌患者是否常規(guī)行后腹膜淋巴結(jié)切除一直存在爭議,本綜述將對(duì)有關(guān)子宮內(nèi)膜癌淋巴結(jié)切除的文獻(xiàn)進(jìn)行選擇性述評(píng),主要圍繞后腹膜淋巴結(jié)切除的臨床價(jià)值、適應(yīng)癥,切除范圍、并發(fā)癥,,如何預(yù)測淋巴結(jié)轉(zhuǎn)移等方面展開論述。最終得出的結(jié)論是:大多數(shù)研究證實(shí)后腹膜淋巴結(jié)切除對(duì)淋巴結(jié)轉(zhuǎn)移低風(fēng)險(xiǎn)的患者無改善生存率的作用,而對(duì)中高風(fēng)險(xiǎn)的子宮內(nèi)膜癌患者有提高生存率的作用,并對(duì)術(shù)后輔助治療起到指導(dǎo)作用。同時(shí)關(guān)于前哨淋巴結(jié)切除的研究還處于初級(jí)階段,尚不能代替系統(tǒng)性淋巴結(jié)切除術(shù)。
[Abstract]:Endometrial carcinoma is one of the most common gynecological tumors. Since 1988, Figo stage has changed from clinical stage to operation-pathological stage. The standard operative staging includes pelvic lymph node and abdominal aortic lymph node resection. However, there has been controversy about whether early endometrial carcinoma patients should undergo retroperitoneal lymphadenectomy. This review will review the literature on lymph node resection of endometrial carcinoma selectively. The clinical value, indication, resection range, complications of retroperitoneal lymph node resection were mainly discussed. This paper discusses how to predict lymph node metastasis. The final conclusion is that most studies have confirmed that retroperitoneal lymphadenectomy does not improve survival rate in patients with low risk of lymph node metastasis. But it can improve the survival rate of endometrial carcinoma patients with high risk and can guide the postoperative adjuvant therapy. At the same time, the research on sentinel lymph node resection is still in the primary stage, and it is not a substitute for systemic lymphadenectomy.
【學(xué)位授予單位】:上海交通大學(xué)
【學(xué)位級(jí)別】:碩士
【學(xué)位授予年份】:2014
【分類號(hào)】:R737.33

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