【摘要】：目的探討慢性心力衰竭(CHF)患者左心室內(nèi)血流自收縮射血向舒張充盈血流逆轉(zhuǎn)的規(guī)律。資料與方法選取25例CHF患者作為CHF組,并選取28例健康人作為對(duì)照組。測(cè)定射血-充盈血流逆轉(zhuǎn)間期(FRI)、校正射血-充盈血流逆轉(zhuǎn)間期(CFRI)、射血-充盈血流逆轉(zhuǎn)流率(FRR)、左心室射血期峰值流率(FRPE),比較兩組左心室流體力學(xué)參數(shù)的差異。結(jié)果與對(duì)照組相比,CHF患者左心室渦流FRI延長(zhǎng)[(71±13)ms對(duì)(113±30)ms,P0.05)],FRR減低[(46.85±21.35)cm2/s對(duì)(27.90±16.77)cm2/s,P0.05)],FRPE減低[(74.54±9.10)cm2/s對(duì)(41.12±17.25)cm2/s,P0.05)]。FRI、CFRI與Tei指數(shù)呈正相關(guān)(r=0.812、0.849,P0.01),FRI與左心室射血分?jǐn)?shù)(LVEF)、短軸縮短率(FS)、每搏量(SV)、心輸出量(CO)、心指數(shù)(CI)呈負(fù)相關(guān)(r=-0.646~-0.515,P0.05、P0.01);CFRI與LVEF、FS、SV、CO、CI呈負(fù)相關(guān)(r=-0.685~-0.456,P0.05、P0.01);FRR與Tei指數(shù)呈負(fù)相關(guān)(r=-0.604,P0.05),與LVEF、FS、SV、CO、CI呈正相關(guān)(r=0.503~0.812,P0.05、P0.01);FRPE與Tei指數(shù)呈負(fù)相關(guān)(r=-0.734,P0.01),與LVEF、FS、SV、CO、CI呈正相關(guān)(r=0.557~0.776,P0.05、P0.01)。結(jié)論超聲血流向量成像能夠直觀地顯示并定量分析CHF患者左心室的流體力學(xué)變化,左心室內(nèi)血流方向逆轉(zhuǎn)效率可以作為判斷CHF治療效果的指標(biāo)之一。
[Abstract]:Objective to investigate the reversal of left ventricular autocontractile ejection to diastolic filling in patients with chronic heart failure (CHF). Materials and methods 25 CHF patients were selected as CHF group and 28 healthy persons as control group. (FRI), correction of ejection-filling reversal interval (CFRI), ejection-flow reversal rate (FRR), left ventricular peak flow rate (FRPE), To compare the difference of left ventricular hydrodynamic parameters between the two groups. Results compared with the control group, left ventricular eddy current FRI prolonged [(71 鹵13) ms vs (113 鹵30) ms,P0.05], FRR decreased [(46.85 鹵21.35) cm2/s vs (27.90 鹵16.77) cm2/s,P0.05] in CHF patients. FRPE decreased [(74.54 鹵9.10) cm2/s vs (41.12 鹵17.25) cm2/s,P0.05]. There was a positive correlation between FRI,CFRI and Tei index (r = 0.812 鹵0.849), FRI and (LVEF), short axis shortening rate of left ventricular ejection fraction (FS),). There was a negative correlation between (CO), and (CI) in (SV), cardiac output per stroke volume (r = -0.646 ~ (-0.515) P _ (0.05) P _ (0.01). There was a negative correlation between CFRI and LVEF,FS,SV,CO,CI (r = -0.685U -0.456N, P 0.05, P 0.01). There was a negative correlation between FRR and Tei index (r = 0.604, P 0.05), and a positive correlation between FRR and LVEF,FS,SV,CO,CI (r = 0.503n, 0.812, P 0.05, P 0.01). There was a negative correlation between FRPE and Tei index (r = -0.734, P 0.01), and a positive correlation between FRPE and LVEF,FS,SV,CO,CI (r = 0.557, P = 0.776, P 0.05, P 0.01). Conclusion Ultrasound flow vector imaging can directly display and quantitatively analyze the changes of left ventricular fluid dynamics in patients with CHF, and the reversal efficiency of left ventricular flow direction can be used as an index to judge the therapeutic effect of CHF.
【作者單位】： 同濟(jì)大學(xué)附屬東方醫(yī)院心血管超聲科;唐山市玉田縣醫(yī)院彩超室;大慶龍南醫(yī)院物理診斷B超室;
【基金】：浦東新區(qū)科技發(fā)展基金創(chuàng)新項(xiàng)目(PKJ2010-Y16)
【分類(lèi)號(hào)】：R445.1;R541.6

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