發(fā)布時(shí)間：2018-08-22 14:19

【摘要】：目的探討單次屏氣單次激發(fā)相位重聚梯度回波相位對(duì)比反轉(zhuǎn)恢復(fù)序列(single shot true-FISPPSIR)與多次屏氣k空間節(jié)段填充快速擾相梯度回波相位對(duì)比反轉(zhuǎn)恢復(fù)序列(segmented-turbo-FLASH-PSIR)在心臟磁共振增強(qiáng)掃描(CE-CMR)中定性及定量評(píng)價(jià)心肌梗死的比較優(yōu)勢(shì)。方法納入臨床診斷心肌梗死并行心臟磁共振增強(qiáng)檢查的患者38例,按標(biāo)準(zhǔn)掃描方案,在完成心肌首過(guò)灌注(釓對(duì)比劑,0.15mmol/kg)12~20min后行心肌延遲掃描。分別采用single shot true-FISP-PSIR和segmented-turbo-FLASH-PSIR兩種延遲掃描方案完成左心室短軸掃描。比較兩種序列圖像的質(zhì)量,并采用心臟磁共振圖像分析軟件(Q-mass,Medis)自動(dòng)測(cè)量每位患者的梗死心肌體積和梗死心肌比例(ratio),比較兩種不同序列對(duì)于定量評(píng)價(jià)梗死心肌體積和比例的差異。結(jié)果所有患者均成功完成所有掃描。兩種序列采集的心肌延遲強(qiáng)化圖像對(duì)比度噪聲比差異無(wú)統(tǒng)計(jì)學(xué)意義(P0.05);兩種序列間左室心肌總體積差異無(wú)統(tǒng)計(jì)學(xué)意義(P0.05),同時(shí)single shot true-FISP-PSIR梗死心肌體積〔(30.87±15.72)mL〕及梗死心肌比例(22.94%±10.94%)與segmented-turbo-FLASH-PSIR相比〔(29.26±14.07)mL,(20.75%±8.78%)〕,差異無(wú)統(tǒng)計(jì)學(xué)意義(P0.05);但前者平均采集時(shí)間(20.4s)短于后者(380s)。結(jié)論Single shot true-FISP-PSIR心臟磁共振延遲掃描技術(shù)能夠?qū)崿F(xiàn)單次屏氣的準(zhǔn)確的心肌梗死范圍的定量評(píng)價(jià),與常規(guī)segmented-turbo-FLASH-PSIR序列效果相當(dāng),并能顯著縮短掃描時(shí)間,值得在臨床和研究中應(yīng)用。
[Abstract]:Objective to investigate the effects of phase contrast inversion recovery sequence (single shot true-FISPPSIR) and phase contrast inversion recovery sequence (segmented-turbo-FLASH-PSIR) on phase contrast gradient echo (segmented-turbo-FLASH-PSIR) of single breath-holding phase reentrant gradient echo (segmented-turbo-FLASH-PSIR) in cardiac magnetic resonance imaging (Mr). Quantitative and qualitative evaluation of myocardial infarction in contrast enhanced scanning (CE-CMR). Methods Thirty-eight patients with myocardial infarction and cardiac magnetic resonance enhanced examination were included. According to the standard scan scheme, myocardial delayed scanning was performed after completion of myocardial first-pass perfusion (gadolinium contrast agent 0.15 mmol / kg) 12~20min. Left ventricular short-axis scanning was performed by single shot true-FISP-PSIR and segmented-turbo-FLASH-PSIR. The quality of the two sequences was compared, and the volume and ratio of infarcted myocardium were measured automatically by using Q-mass-Medis software. The difference of the volume and proportion of infarcted myocardium was compared between the two sequences in quantitative evaluation of infarct myocardial volume and ratio. Results all the patients completed all the scans successfully. There was no significant difference in contrast noise ratio between the two sequences (P0.05), but there was no significant difference in the total left ventricular volume between the two sequences (P0.05), while the infarcted myocardial volume of single shot true-FISP-PSIR was (30.87 鹵15.72) mL) and that of the infarcted myocardium was (30.87 鹵15.72) mL). Ratio (22.94% 鹵10.94%) compared with segmented-turbo-FLASH-PSIR (29.26 鹵14.07) mL, (20.75% 鹵8.78%),) The difference was not statistically significant (P0.05), but the average acquisition time of the former (20.4s) was shorter than that of the latter (380s). Conclusion Single shot true-FISP-PSIR cardiac magnetic resonance delayed scanning technique can achieve accurate quantitative evaluation of myocardial infarction size with single breath-holding, which is comparable to that of conventional segmented-turbo-FLASH-PSIR sequence, and can significantly shorten the scanning time. It is worthy of clinical application and research.
【作者單位】： 四川大學(xué)華西醫(yī)院放射科;四川大學(xué)華西醫(yī)院心內(nèi)科;中國(guó)科學(xué)院深圳先進(jìn)技術(shù)研究院;
【基金】：國(guó)家自然科學(xué)基金(No.81271531)資助
【分類(lèi)號(hào)】：R445.2;R542.22

【共引文獻(xiàn)】

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