本文選題：超聲造影 + 乳腺腫塊��； 參考：《重慶醫(yī)科大學(xué)》2014年碩士論文

【摘要】：目的：總結(jié)乳腺良惡性病灶超聲造影特點(diǎn)，探討超聲造影技術(shù)在乳腺良惡性腫塊中的鑒別診斷價(jià)值。 方法：對(duì)2013年3月~2013年11月我院107例乳腺腫塊患者進(jìn)行超聲造影檢查，對(duì)腫塊的增強(qiáng)方式及時(shí)間-強(qiáng)度曲線進(jìn)行分析，總結(jié)乳腺良惡性腫塊的超聲造影特點(diǎn)。 結(jié)果：病理診斷93個(gè)病灶，其中惡性52個(gè)，良性41個(gè)。52個(gè)惡性病灶中，47個(gè)表現(xiàn)為不均勻增強(qiáng)(90.38％)，39個(gè)表現(xiàn)為高增強(qiáng)(75.0%),增強(qiáng)后邊界均顯示不清（100％），其中32個(gè)病灶見造影劑滯留（61.54％），23個(gè)病灶見穿支血管顯影（44.23％）。41個(gè)良性病灶中，32個(gè)病灶表現(xiàn)為均勻增強(qiáng)(78.05%)，增強(qiáng)程度以等增強(qiáng)和低增強(qiáng)為主，亦可有高增強(qiáng)、無(wú)增強(qiáng)。28個(gè)病灶增強(qiáng)后邊界清楚（68.30%），，35個(gè)病灶無(wú)造影劑滯留（85.37%），38個(gè)病灶無(wú)穿支血管（92.68%）。時(shí)間-強(qiáng)度曲線中惡性病灶呈現(xiàn)快速上升后緩慢階梯狀下降，良性病灶呈現(xiàn)快速上升后迅速下降，惡性病灶時(shí)間-強(qiáng)度曲線開始增強(qiáng)時(shí)間（Wash-in-time）較良性早，峰值強(qiáng)度（Peak intensity）較良性病灶大，惡性組開始增強(qiáng)時(shí)間(10.56±3.78s)、峰值強(qiáng)度（36.20±15.18dB）與良性組比較差異具有統(tǒng)計(jì)學(xué)意義（P＜0.05）。惡性組與良性組達(dá)峰時(shí)間（Time to peak）、峰值強(qiáng)度減半時(shí)間（Half of Peakintensity）分別比較，兩者間差異無(wú)統(tǒng)計(jì)學(xué)意義（P＞0.05）。 結(jié)論：通過(guò)超聲造影發(fā)現(xiàn)乳腺良惡性病灶增強(qiáng)模式具有一定特征性表現(xiàn)，結(jié)合造影時(shí)間-強(qiáng)度曲線分析有助于對(duì)乳腺良惡性腫瘤的鑒別診斷。
[Abstract]:Objective: to summarize the contrast-enhanced features of benign and malignant breast lesions and to evaluate the value of contrast-enhanced ultrasonography in differential diagnosis of benign and malignant breast masses. Methods: from March 2013 to November 2013, 107 patients with breast masses in our hospital were examined by contrast-enhanced ultrasonography. The enhancement mode and time-intensity curve of breast masses were analyzed, and the contrast-enhanced features of benign and malignant breast masses were summarized. Results: 93 lesions were diagnosed by pathology, of which 52 were malignant. Of the 41 benign and 52 malignant lesions, 47 showed heterogeneous enhancement (90.38%), 39 showed high enhancement (75.0%), and the boundary of enhancement showed 100% indistinct. Of these, 32 lesions showed contrast agent retention (61.54), 23 lesions showed perforator vessel imaging and 41 benign lesions. Among them, 32 lesions showed homogeneous enhancement (78.05), and the degree of enhancement was mainly equal enhancement and low enhancement. There were also high enhancement and no enhancement. After enhancement, 28 lesions had clear boundary 68.30, 35 lesions had no contrast agent, and 38 lesions had no perforating vessels 92.68%. In the time-intensity curve, the malignant lesions showed a rapid rise and then a slow step down, and the benign lesions showed a rapid rise and then a rapid decline, and the time of enhancement of the malignant lesions began to be Wash-in-time earlier than that of the benign lesions. The peak intensity of peak intensity was larger than that of benign lesions. The time of enhancement was 10.56 鹵3.78 s-1, and the peak intensity was 36.20 鹵15.18 dB. There was significant difference between malignant group and benign group (P < 0.05). There was no significant difference between malignant group and benign group (P > 0.05). Conclusion: contrast-enhanced mode of benign and malignant breast lesions is characteristic by contrast-enhanced ultrasonography. The analysis of time-intensity curve is helpful to the differential diagnosis of breast benign and malignant tumors.
【學(xué)位授予單位】：重慶醫(yī)科大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2014
【分類號(hào)】：R445.1

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