【摘要】：目的：探討不同方案治療小兒病毒性肺炎痰熱閉肺證的臨床療效。 方法：將130例病毒性肺炎患兒隨機(jī)分為三組：A組50例，予喜炎平注射液（5～10mg/kg·d）加入5%葡萄糖注射液或0.9%氯化鈉溶液100ml靜滴，中藥五虎湯合葶藶大棗瀉肺湯加減口服；B組50例，予喜炎平注射液5～10mg/（kg·d）加入5%葡萄糖注射液或0.9%氯化鈉溶液100ml靜滴，小兒清肺合劑(0.5～1歲10ml1+～3歲15ml3+～5歲20ml)、化痰散(0.5～1歲0.5g1+～3歲1.5g3+～5歲2.0g)口服，敷胸散（大黃：芒硝：蒜泥=4:1:4）50mg外敷背部雙肺羅音明顯處；C組30例，利巴韋林（10～15mg/kg·d）加入5%葡萄糖注射液或0.9%氯化鈉溶液100ml靜滴，愈酚甲麻那敏糖漿（0.5～1歲3ml1+～3歲5ml3+～5歲8ml）口服。 結(jié)果：三組患兒治療結(jié)束后總積分與治療前相比均有明顯減少，經(jīng)統(tǒng)計(jì)學(xué)分析，有非常顯著性差異（P=0.000）；其中，A組總有效率98%，B組總有效率96%，C組總有效率80%，A、B兩組總療效相當(dāng)（P0.05），均優(yōu)于C組（P0.05）。在單個(gè)癥狀、體征比較上，A、B組中咳嗽、咯痰、喘促、肺部羅音的平均恢復(fù)時(shí)間優(yōu)于C組；治療結(jié)束后，A、B兩組在改善發(fā)熱、咯痰、咳嗽、肺部羅音方面均優(yōu)于C組，A組在平喘方面優(yōu)于C組（P0.05）。 結(jié)論：三種方案均能有效治療小兒病毒性肺炎痰熱閉肺證；其中，A、B兩組療效相當(dāng)，優(yōu)于C組，說(shuō)明喜炎平配合中藥（中成藥）治療本病較西藥利巴韋林效果更好，，能有效改善臨床癥狀、體征，具有應(yīng)用價(jià)值。
[Abstract]:Objective: to explore the clinical effect of different regimens on infantile viral pneumonia with phlegm-heat closed lung syndrome. Methods: 130 children with viral pneumonia were randomly divided into three groups: group A (50 cases) received Xiyanping injection (5~10mg/ kg 路d) plus 5% glucose injection or 0.9% sodium chloride solution 100ml intravenous drip. Traditional Chinese medicine Wuhu decoction combined with Draba jujube Xiefei decoction reduced oral; Group B (50 cases) received Xiyanping injection 5~10mg/ (kg 路d) plus 5% glucose injection or 0.9% sodium chloride solution 100ml intravenous drip. Xiaoer Qingfei mixture (0. 5-1-year-old 10ml1-3-year-old 15ml3-5-year-old 20ml) was given. Huatan powder (0.5-1-year-old 0.5g1-3-year-old 1.5g3-5 years old 2.0 g) was given orally and chest powder (rhubarb: mirabilite: garlic mashed = 4:1:4) 50mg was applied on the back of both lungs. Group C (n = 30) was treated with ribavirin (10~15mg/ kg 路d) with 5% glucose injection or 0.9% sodium chloride solution (100ml). Guaifen-methylmanamine syrup (3ml1-3-year-old 5ml3-5-year-old 8ml) was given orally. Results: after treatment, the total scores of the three groups decreased significantly compared with those before treatment, and there was a significant difference between the three groups (P < 0. 000). The total effective rate was 98% in group A, 96% in group B, 80% in group C, and the total effective rate in group A and B was similar (P0.05), which was better than that in group C (P0.05). The average recovery time of cough, expectoration, wheezing and lung rales in group A and B was better than that in group C on the comparison of single symptom and physical sign. After treatment, group A and B were better than group C in improving fever, expectoration, cough and lung rales, and group A was better than group C in relieving asthma (P0.05). Conclusion: all three schemes can effectively treat the syndrome of phlegm-heat closed lung in children with viral pneumonia. The results showed that Xiyanping combined with traditional Chinese medicine (Chinese patent medicine) was more effective in treating this disease than that of western medicine ribavirin, which could effectively improve the clinical symptoms and signs, and had practical value in the treatment of this disease. The results showed that Xiyanping combined with traditional Chinese medicine was more effective than ribavirin in the treatment of this disease.
【學(xué)位授予單位】：山東中醫(yī)藥大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2014
【分類號(hào)】：R272

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