【摘要】：目的評估生長抑素應用于小兒腹部手術(shù)后的臨床療效和安全性。方法該研究共納入2014年1月-2016年6月在海南省人民醫(yī)院行腹部手術(shù)的急腹癥患兒120例,將其隨機分為觀察組(60例)和對照組(60例)。腹部手術(shù)后,對照組給予常規(guī)治療。觀察組在常規(guī)治療基礎(chǔ)上聯(lián)合應用生長抑素。比較兩組患兒的腹圍差、術(shù)后24h胃腸管引流和嘔吐量、肛門排氣時間、住院時間等術(shù)后情況;比較兩組患兒術(shù)后并發(fā)癥的發(fā)生率、生活質(zhì)量評分,以及患兒和家長對治療的滿意度。結(jié)果觀察組患兒的腹圍差、24 h胃腸管引流和嘔吐量、肛門排氣時間及住院時間少于對照組(P0.05)。觀察組患兒術(shù)后并發(fā)癥發(fā)生率為6.7%,低于對照組患兒術(shù)后并發(fā)癥發(fā)生率(18.3%)(P0.05)。兩組患兒術(shù)前生活質(zhì)量評分比較,差異無統(tǒng)計學意義(P0.05)。術(shù)后1個月,兩組患兒的生活質(zhì)量評分較術(shù)前提高(P0.05)。而且觀察組患兒術(shù)后生活質(zhì)量評分高于對照組(P0.05)。觀察組患兒和家長對治療的滿意度為96.7%,高于對照組(81.7%)(P0.05)。結(jié)論小兒腹部手術(shù)后應用生長抑素能夠有效促進患兒術(shù)后胃腸功能的恢復,改善預后,提高生活質(zhì)量。
[Abstract]:Objective to evaluate the clinical efficacy and safety of somatostatin after abdominal surgery in children. Methods A total of 120 children with acute abdomen underwent abdominal surgery in Hainan Provincial people's Hospital from January 2014 to June 2016 were randomly divided into observation group (n = 60) and control group (n = 60). After abdominal operation, the control group was given routine treatment. The observation group was treated with somatostatin on the basis of routine therapy. The abdominal circumference, gastrointestinal tube drainage and vomiting, anal exhaust time and hospitalization time were compared between the two groups, and the incidence of postoperative complications and quality of life score were compared between the two groups. And the satisfaction of children and parents with the treatment. Results the amount of gastrointestinal tube drainage and vomiting, anal exhaust time and hospitalization time in the observation group were less than those in the control group (P0.05). The incidence of postoperative complications in the observation group was 6. 7%, which was lower than that in the control group (18. 3%) (P0.05). There was no significant difference in preoperative quality of life score between the two groups (P0.05). One month after operation, the scores of quality of life in the two groups were higher than those before operation (P 0.05). Moreover, the quality of life score in the observation group was higher than that in the control group (P0.05). The satisfaction of children and parents in the observation group was 96.7%, which was higher than that in the control group (81.7%) (P0.05). Conclusion the application of somatostatin after abdominal operation in children can effectively promote the recovery of gastrointestinal function, improve prognosis and improve the quality of life.
【作者單位】： 海南省人民醫(yī)院小兒外科;
【分類號】：R726.5

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