【摘要】：目的探討外貌評分與女性青少年系統(tǒng)性紅斑狼瘡(systemic lupus erythematosus, SLE)患者抑郁癥狀之間的關(guān)系。 方法選取42名青少年女性SLE患者作為患者組,40名年齡段相同的女性受試者作為對照組,對患者組及對照組受試者實施問卷調(diào)查。調(diào)查內(nèi)容包括系統(tǒng)性紅斑狼瘡疾病活動性指數(shù)(systemic lupus erythematosis disease activity index, SLEDAI)量表評價SLE疾病嚴重程度,兒童抑郁量表(children's depression inventory, CDI)評價兒童抑郁情況,兒童自我感知量表(self-perception profile for children, SPPC)中的外貌評價項目進行外貌評分。所有的分析均采用SPSS10.0進行數(shù)據(jù)分析。t檢驗比較正態(tài)分布數(shù)據(jù)差異,Spearman相關(guān)分析進行相關(guān)性研究,多分類有序Logistic回歸分析,p0.05定義為顯著性差異,檢驗水準α=0.05。 結(jié)果患者組中幾乎所有的患者均表現(xiàn)出不同程度的抑郁癥狀�；颊呓MCDI總分平均為18.5±4.3,38.1%(16／42)的患者CDI大于19分。對照組CDI分數(shù)顯著低于患者組(11.4±1.7vs.18.54±4.3,p0.05)。92.9%(39／42)的SLE患者表示因為SLE而變得對自身相貌不滿意。這些患者中,SPPC外貌得分為13.0±2.8,而對照組兒童外貌評價得分為20.0±3.1(p0.05)。單因素Pearson相關(guān)分析評價年齡、病程、SLEDAI評分、住院次數(shù)、外貌評分及CDI評分之間的關(guān)系。外貌評分與抑郁癥狀高度相關(guān)(r=-0.758,p=0.001),其他因素如病程、SLEDAI評分及住院次數(shù)儀與抑郁癥狀部分相關(guān)。狼瘡腦病組患兒與非狼瘡腦病組患兒抑郁癥狀發(fā)病率無顯著區(qū)別。 結(jié)論外貌改變與青少年女性SLE患者出現(xiàn)抑郁癥狀有較為顯著的相關(guān)性,提示我們在治療時應(yīng)充分重視緩解與外貌相關(guān)的癥征,盡可能減少各種治療對外貌帶來的影響,并應(yīng)加強此方面的心理輔導(dǎo)。此外,狼瘡腦病與患兒抑郁癥狀無顯著關(guān)聯(lián)。
[Abstract]:Objective to investigate the relationship between appearance score and depressive symptoms in female adolescent patients with systemic lupus erythematosus (systemic lupus erythematosus, SLE). Methods 42 adolescent female SLE patients were selected as the control group and 40 female subjects of the same age group as the control group. The subjects in the patient group and the control group were investigated by questionnaire. The contents of the investigation included the evaluation of the severity of SLE disease with the activity index of systemic lupus erythematosus (systemic lupus erythematosis disease activity index, SLEDAI) and the evaluation of depression in children with (children's depression inventory, CDI). Children's self-perception scale (self-perception profile for children, SPPC) was used to evaluate appearance. All the analyses were carried out by SPSS10.0 data analysis. T test was used to compare the normal distribution data difference and Spearman correlation analysis. The multi-classification ordered Logistic regression analysis was defined as significant difference, and the test level was 偽 0.05. Results almost all patients in the patient group showed different degree of depression. The average total score of CDI in patients was 18.5 鹵4.3 鹵38.1% (16 / 42), CDI was greater than 19. CDI scores in the control group were significantly lower than those in the patient group (11.4 鹵1.7vs.18.54 鹵4.3 p0.05). 92.9% (39 / 42) of SLE patients indicated that they were not satisfied with their appearance because of SLE. In these patients, the SPPC appearance score was 13.0 鹵2.8, while that in the control group was 20.0 鹵3.1 (p0.05). Univariate Pearson correlation analysis was used to evaluate the relationship between age, course of disease and SLEDAI score, hospitalization frequency, appearance score and CDI score. There was a high correlation between appearance score and depression symptoms (r = -0.758p0. 001). Other factors, such as the SLEDAI score of course of disease and the frequency of hospitalization, were partly related to depression symptoms. There was no significant difference in the incidence of depressive symptoms between children with lupus encephalopathy and those with non-lupus encephalopathy. Conclusion there is a significant correlation between appearance changes and depressive symptoms in adolescent female SLE patients, which suggests that we should pay more attention to alleviating the symptoms associated with appearance and minimize the effects of various treatments on appearance. Psychological counseling in this area should be strengthened. In addition, there was no significant association between lupus encephalopathy and depressive symptoms in children.
【學(xué)位授予單位】：北京協(xié)和醫(yī)學(xué)院
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2012
【分類號】：R725.9

【參考文獻】

相關(guān)期刊論文 前10條

1 吳小川,易著文,劉哲寧,劉鐵橋,張星星,黨西強;腎病綜合征急性腎炎患兒及家長心理衛(wèi)生狀況初步研究[J];中國當(dāng)代兒科雜志;2001年02期

2 劉敏娜;黃鋼;章小雷;;結(jié)構(gòu)式集體游戲治療對10～11歲學(xué)習(xí)困難兒童的心理干預(yù)研究[J];中國兒童保健雜志;2007年05期

3 易歡瓊,徐斯玲 ,司徒素琴 ,周建平;小學(xué)生心身疾患和焦慮問題分析[J];健康心理學(xué)雜志;2002年01期

4 呂波,梁星群;兒童哮喘綜合治療管理與心理影響研究[J];臨床兒科雜志;2001年01期

5 牟肇蓉,傅以容,肖曉陽;重慶市獨生子女心理健康調(diào)查[J];臨床精神醫(yī)學(xué)雜志;2000年05期

6 李永紅;李鐘洙;林維嘉;吳泳;;系統(tǒng)性紅斑狼瘡165例臨床分析[J];中國麻風(fēng)皮膚病雜志;2007年05期

7 黃健寧;曾夏杏;武革;;系統(tǒng)性紅斑狼瘡患者的心理障礙因素及護理干預(yù)[J];內(nèi)科;2007年03期

8 欒奕;陳健鵬;;兒童與成年人系統(tǒng)性紅斑狼瘡臨床對比分析[J];實用醫(yī)藥雜志;2010年08期

9 王堅杰;張洪波;;兒童青少年心理健康促進研究進展[J];中國婦幼健康研究;2006年03期

10 王淑燕;董俊花;;父母教養(yǎng)方式與礦工子女學(xué)業(yè)自我效能感的關(guān)系[J];通化師范學(xué)院學(xué)報;2011年01期

，

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