本文選題：-羥基維生素D + 維生素D缺乏�。� 參考：《中國當代兒科雜志》2017年07期

【摘要】：目的分析早產(chǎn)兒出生時維生素D水平及其可能影響因素。方法采集600例早產(chǎn)兒出生24 h內(nèi)靜脈血,檢測血清25-羥基維生素D[25(OH)D]水平,并分析早產(chǎn)兒性別、出生體重、出生季節(jié)、胎齡,以及母親的年齡、職業(yè)、早孕期體重指數(shù)(BMI)、分娩方式及妊娠期并發(fā)癥等對血清25(OH)D水平的影響。結(jié)果早產(chǎn)兒維生素D缺乏、不足、充足的比例分別為42.0%、38.7%和19.3%。夏、秋季出生的早產(chǎn)兒血清25(OH)D水平顯著高于冬季(P0.05),維生素D缺乏的發(fā)生率顯著低于春、冬季(P0.003)。與母親年齡≥30歲者比較,年齡30歲母親所生早產(chǎn)兒血清25(OH)D水平顯著降低(P0.05),維生素D缺乏的發(fā)生率顯著增高(P0.017)。與母親肥胖者比較,超重或體重正常母親所生早產(chǎn)兒血清25(OH)D水平顯著增高(P0.05),維生素D缺乏的發(fā)生率顯著降低(P0.006)。母親妊娠合并子vN前期者,其早產(chǎn)兒血清25(OH)D水平顯著低于無子vN前期者(P0.05),維生素D缺乏的發(fā)生率顯著高于無子vN前期者(P0.017)。多因素分析結(jié)果顯示,冬春季出生、母親年齡30歲及早孕期BMI≥28 kg/m2為早產(chǎn)兒維生素D缺乏的危險因素(P0.05)。結(jié)論早產(chǎn)兒維生素D缺乏發(fā)生率較高,有維生素D缺乏高危因素的早產(chǎn)兒生后需盡早補充維生素D。
[Abstract]:Objective to analyze the level of vitamin D at birth of premature infants and its possible influencing factors. Methods the venous blood samples were collected from 600 premature infants within 24 hours of birth. The serum levels of 25-hydroxyvitamin D [25 (OH) D] were measured, and the sex, birth weight, birth season, gestational age, age and occupation of preterm infants were analyzed. The serum 25 (OH) D level of premature infants born in summer and autumn was significantly higher than that in winter (P0.05), and the incidence of vitamin D deficiency was significantly lower than that in spring and winter (P0.003). Compared with obese mothers, the serum 25 (OH) D level of preterm infants born to overweight or normal mothers was significantly higher (P0.05), and the incidence of vitamin D deficiency was significantly lower (P0.006). The serum levels of 25 (OH) D in preterm infants were significantly lower than those without vN (P0.05), and the incidence of vitamin D deficiency was significantly higher than that in those without vN (P0.017). The results of multivariate analysis showed that birth in winter and spring and maternal age 鈮，

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