本文關鍵詞：新生兒高膽紅素血癥相關影響因素分析　出處：《新疆醫(yī)科大學》2013年碩士論文　論文類型：學位論文

  更多相關文章： 新生兒高膽紅素血癥 危險因素 Logistic回歸分析

【摘要】：目的：探討新生兒高膽紅素血癥（高膽）相關影響因素，為臨床預防及治療新生兒高膽紅素血癥提供臨床依據。方法：調查2011—2012年新疆醫(yī)科大學第一附屬醫(yī)院5023例新生兒（產科新生兒4442例及新生兒科高膽紅素血癥病例581例），進行回顧性及描述性分析，根據Logistic回歸分析其影響因素。結果：1.二分類Logistic回歸分析示：民族、胎齡、出生體重為新生兒高膽紅素血癥保護因素（P0.05，β均0，分別為-0.387、-0.446、-1.011,exp(β)均1，分別為0.473、0.246、0.016）;胎膜早破、頭顱血腫、喂養(yǎng)方式、母子血型不合、開奶時間、同胞中有高膽紅素血癥為新生兒高膽紅素血癥危險因素（P0.05，β均0,分別為0.334、0.346、0.889、0.591、0.476、1.889，,exp(β)均1，1.715、1.413、2.434、1.453、1.460、1.843）。2.將新生兒高膽紅素血癥作為研究組，分為輕中度組、重度組，對照組為非高膽紅素血癥新生兒，進行多元Logistic分析顯示：胎齡和出生體重為新生兒高膽紅素血癥保護性因素（P0.05,β均0,分別為-0.443、-1.011，exp(β)均1，分別為0.441、0.016），母子血型不合、開奶時間、同胞中高膽紅素血癥、胎膜早破為其病情嚴重程度的危險因素（P0.05,β均0,分別為1.673、1.361、1.657、0.452，exp(β)均1，分別為1.673、1.361、2.113、1.822）；3.民族中維族、哈族新生兒高膽紅素血癥發(fā)病率低（P0.05），喂養(yǎng)方式中人工及混合喂養(yǎng)較母乳喂養(yǎng)新生兒高膽紅素血癥發(fā)病率低（P0.05）；結論：新生兒高膽紅素血癥是新生兒常見疾病，發(fā)病率高，與多種相關因素有關，根據相關危險因素積極治療制定診治方案，積極預防感染，重視產前相關檢查及生后膽紅素監(jiān)測，，減少高膽發(fā)病率，尤其重癥高膽紅素血癥發(fā)病率，降低高膽紅素血癥對新生兒生長發(fā)育影響。
[Abstract]:Objective: to investigate the related factors of neonatal hyperbilirubinemia (hyperbilirubinemia). Methods: a survey of 5023 neonates with neonatal hyperbilirubinemia in the first affiliated Hospital of Xinjiang Medical University from 2011 to 2012 was conducted to provide clinical evidence for the prevention and treatment of neonatal hyperbilirubinemia. 4442 cases of obstetrical newborns and 581 cases of neonatal hyperbilirubinemia. Retrospective and descriptive analysis were carried out. According to the Logistic regression analysis, the influencing factors were analyzed. Results the Logistic regression analysis showed that: nationality, gestational age. Birth weight was the protective factor of neonatal hyperbilirubinemia (P0.05, 尾 0, respectively, -0.387- 0.446- 1.011exp1). It was 0.473U (0.246) and 0.016m (P < 0.05). Premature rupture of membranes, cranial hematoma, feeding mode, blood group incompatibility between mother and child, time of milk opening, hyperbilirubinemia in sibling were risk factors of hyperbilirubinemia in newborn (P 0.05, 尾 0). The values were 0.334U 0.346U 0.889U 0.591U 0.476U 1.889U expp (尾) 1.715U 1.413132.434, respectively. The neonatal hyperbilirubinemia was divided into mild and moderate group, severe group, and control group as non-hyperbilirubinemia neonates. Multivariate Logistic analysis showed that gestational age and birth weight were the protective factors of neonatal hyperbilirubinemia (P0.05, 尾 0, respectively, -0.443 鹵1.011). Expat (尾) were 1, respectively, were 0.441 ~ 0.016, blood group incompatibility, milk opening time, sibling hyperbilirubinemia. Premature rupture of membranes was the risk factor for the severity of the disease (P 0.05, 尾 = 0, respectively, 1.673U 1.361U 1.657U 0.452exp1). 1.673U 1.361C 2.113U 1.822m; 3.The incidence of neonatal hyperbilirubinemia in Uygur and Kazakh nationalities was lower than that in breast-fed neonates (P 0.05), and the incidence of hyperbilirubinemia was lower in artificial and mixed feeding than in breast-fed neonates. Conclusion: neonatal hyperbilirubinemia is a common disease of newborns with high incidence, which is related to many related factors. According to the related risk factors, active treatment and diagnosis and treatment are made to prevent infection. To reduce the incidence of hyperbilirubinemia, especially severe hyperbilirubinemia, and reduce the influence of hyperbilirubinemia on the growth and development of newborn, we should pay attention to prenatal examination and postnatal bilirubin monitoring.
【學位授予單位】：新疆醫(yī)科大學
【學位級別】：碩士
【學位授予年份】：2013
【分類號】：R722.1

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本文編號：1408797