本文選題：脂肪和肥胖相關(guān)基因　切入點(diǎn)：FTO基因　出處：《西南農(nóng)業(yè)學(xué)報(bào)》2017年11期

【摘要】：【目的】本文探討了FTO基因多態(tài)性與不同綿羊群體生長(zhǎng)性狀的相關(guān)性�！痉椒ā坎捎蔑w行質(zhì)譜技術(shù)檢測(cè)了FTO基因在杜泊羊和灘寒雜交群體中的多態(tài)性及其與生長(zhǎng)性狀的相關(guān)性�！窘Y(jié)果】FTO基因的rs160915957位點(diǎn)的AA基因型個(gè)體體重在杜泊和灘寒綿羊群體中分別為極顯著(P0.01)和顯著(P0.05)低于GG型個(gè)體。GG型綿羊胸圍最大,且GG型杜泊羊胸圍顯著大于灘寒羊GG型個(gè)體(P0.05)。GG型個(gè)體在2個(gè)群體中的體斜長(zhǎng)最大,同一群體不同基因型間差異不顯著(P0.05);不同基因型間,灘寒群體綿羊體高大于杜泊羊,但只有AA型個(gè)體在2個(gè)群體間顯著差異(P0.05)。此外,GG型個(gè)體的杜泊羊胸寬最大,AA型的最小,這與灘寒群體相反,但均沒(méi)有顯著性差異(P0.05)。FTO基因的rs160915957位點(diǎn)不同基因型對(duì)綿羊其他性狀的影響差異不顯著�！窘Y(jié)論】FTO基因的rs160915957位點(diǎn)對(duì)杜泊及灘寒綿羊群體的體重、體斜長(zhǎng)及胸圍等具有顯著影響。FTO基因是否是影響綿羊生長(zhǎng)性狀的主效基因尚待進(jìn)一步探討,但FTO基因的rs160915957位點(diǎn)多態(tài)性將為不同綿羊群體后代的體重、胸圍等性狀的選擇提供參考依據(jù)。
[Abstract]:[objective] to investigate the association between FTO gene polymorphism and growth traits of different sheep populations. [methods] the polymorphism of FTO gene in Dupo sheep and Tan cold hybrid population and its relationship with growth were detected by flight mass spectrometry. [results] the weight of AA genotype individuals at rs160915957 locus of FTO gene was significantly lower than that of GG type sheep (P 0.01) and significant P 0.05 (P 0.05), respectively. The chest circumference of GG type Dupo sheep was significantly larger than that of Tan Han sheep (P 0.05). GG type individuals had the largest body oblique length in the two populations, but there was no significant difference between different genotypes of the same population (P 0.05), and among different genotypes, the body height of Tan cold sheep was higher than that of du Bo sheep. However, only the individuals of AA type had significant difference between two populations (P 0.05). In addition, the largest chest width of Dupo sheep in GG individuals was the smallest of AA type, which was contrary to that of cold beach population. However, there was no significant difference in the effect of different genotypes of rs160915957 loci on other traits in sheep. [conclusion] the rs160915957 loci of FTO gene have no significant effect on the body weight of Dupo and Tan Han sheep populations. The effects of body oblique length and chest circumference on whether the FTO gene is the main gene affecting the growth traits of sheep need to be further studied. However, the rs160915957 locus polymorphism of the FTO gene will be the weight of the offspring of different sheep populations. The selection of chest circumference and other traits provides reference basis.
【作者單位】： 寧夏大學(xué)農(nóng)學(xué)院動(dòng)物科學(xué)系;
【基金】：寧夏自然科學(xué)基金(NZ15030)
【分類(lèi)號(hào)】：S826

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