本文選題：輸入性瘧疾 + 流行病學(xué)特征�。� 參考：《中國(guó)寄生蟲(chóng)學(xué)與寄生蟲(chóng)病雜志》2017年02期

【摘要】：目的評(píng)估上海地區(qū)輸入性瘧疾流行病學(xué)特征及重癥瘧疾的危險(xiǎn)因素。方法回顧性收集2013-2015年收治于上海市公共衛(wèi)生臨床中心的輸入性瘧疾病例資料,分析人口學(xué)、流行病學(xué)、實(shí)驗(yàn)室檢查數(shù)據(jù)。組間比較采用Mann-Whitney法和Fisher’s精確檢驗(yàn),logistic回歸分析危險(xiǎn)因素評(píng)估。結(jié)果共收集輸入性瘧疾病例87例,平均發(fā)病年齡為36.4歲,男性82例(94.3%),女性5例(5.7%)。其中中國(guó)患者79例(90.8%),南蘇丹3例(3.4%),印度2例(2.3%),喀麥隆、尼日利亞、布隆迪各1例(1.1%)。在75例能夠明確感染來(lái)源地國(guó)家的病例中,感染來(lái)源地為非洲國(guó)家的多達(dá)63例(84.0%),其次為亞洲(11例,14.7%)。實(shí)驗(yàn)室確診病例78例(89.7%),臨床診斷病例9例(10.3%)。在實(shí)驗(yàn)室確診病例中,感染惡性瘧原蟲(chóng)(Plasmodium falciparum)最多,為66例(84.6%),感染間日瘧原蟲(chóng)(P.vivax)10例(12.8%)。20例(23.0%)患者既往有瘧疾史�；颊甙l(fā)病至住院的中位數(shù)時(shí)間為5 d,30例(34.5%)患者在發(fā)病后的48 h內(nèi)服用抗瘧疾藥物。符合重癥瘧疾標(biāo)準(zhǔn)的18例,其中1例為腦型瘧,17例總膽紅素43μmol/L,3例血清肌酐265μmol/L。多因素logistic回歸分析顯示,發(fā)病后48 h內(nèi)服用抗瘧藥是預(yù)測(cè)重癥瘧疾的獨(dú)立的危險(xiǎn)因子(OR=0.05,95%置信區(qū)間0.01~0.43,P0.05)。結(jié)論惡性瘧原蟲(chóng)是本市輸入性瘧疾病例感染的主要蟲(chóng)種,非洲是主要的感染來(lái)源地。發(fā)病后及時(shí)給予抗瘧治療可降低重癥瘧疾的發(fā)生風(fēng)險(xiǎn)。
[Abstract]:Objective to evaluate the epidemiological characteristics of imported malaria and risk factors of severe malaria in Shanghai. Methods data of imported malaria cases admitted to Shanghai Public Health Clinical Center from 2013 to 2015 were collected retrospectively, and demographic, epidemiological and laboratory data were analyzed. The risk factors were evaluated by Mann-Whitney and Fisher's analysis. Results A total of 87 cases of imported malaria were collected. The average age of onset was 36.4 years old, 82 cases were male, and 5 cases were female. There were 79 cases in China, 3 cases in South Sudan, 2 cases in India, 1 case in Cameroon, 1 case in Nigeria and 1 case in Burundi. Of the 75 cases that could identify the country of origin, 63 cases were from African countries, followed by 11 cases from Asia. 78 cases were diagnosed by laboratory and 9 cases by clinical diagnosis. Among the laboratory confirmed cases, Plasmodium falciparum (66 cases) and P. vivaxae (10 cases) had a history of malaria. The median time from onset to hospitalization was 5 days and 30 patients took antimalarial drugs within 48 hours after onset. Among the 18 patients who met the criteria of severe malaria, one case was cerebral malaria, 17 cases were total bilirubin 43 渭 mol / L, 3 cases were serum creatinine 265 渭 mol 路L ~ (-1). Multivariate logistic regression analysis showed that taking antimalarial drugs within 48 hours after onset was an independent risk factor for predicting severe malaria. Conclusion Plasmodium falciparum is the main infectious species of imported malaria cases in this city, and Africa is the main source of infection. The risk of severe malaria can be reduced by timely antimalarial treatment after onset.
【作者單位】： 復(fù)旦大學(xué)附屬上海市公共衛(wèi)生臨床中心;復(fù)旦大學(xué)附屬華山醫(yī)院;
【分類(lèi)號(hào)】：R181.3;R531.3

【相似文獻(xiàn)】

相關(guān)期刊論文 前10條

1 易正定,楊玉蘭;輸入性瘧疾發(fā)病分析及管理措施[J];中國(guó)寄生蟲(chóng)病防治雜志;2002年05期

2 ;江蘇成為境外輸入性瘧疾發(fā)病率較高的省份之一[J];口岸衛(wèi)生控制;2005年06期

3 葛藤;姜卓;石靜;王曉中;蔡鵬;李云峰;;2005—2012年遼寧口岸輸入性瘧疾流行病學(xué)分析[J];中國(guó)國(guó)境衛(wèi)生檢疫雜志;2013年03期

4 崔鋼;;湖南省加強(qiáng)輸入性瘧疾防治工作[J];中國(guó)寄生蟲(chóng)病防治雜志;1991年03期

5 黃全勇,莊建安,郝家祿;基本消滅瘧疾后輸入性瘧疾暴發(fā)的防治研究[J];現(xiàn)代預(yù)防醫(yī)學(xué);2000年01期

6 柯春榮,段炳華,胡汝源,楊長(zhǎng)貴,彭德峰,馬再偉,母忻隴,代煥珍;一起冬春季輸入性瘧疾爆發(fā)調(diào)查[J];中國(guó)預(yù)防醫(yī)學(xué)雜志;2002年03期

7 劉新,李桂萍,傅斌,趙長(zhǎng)磊,鄧緒禮,陳錫欣,傅兆義,趙中平;山東省輸入性瘧疾的監(jiān)測(cè)與防治[J];中國(guó)寄生蟲(chóng)病防治雜志;2002年03期

8 徐紹山;王冰;魏冰;薛慧麗;;輸入性瘧疾4例流行病學(xué)調(diào)查分析[J];中國(guó)冶金工業(yè)醫(yī)學(xué)雜志;2008年02期

9 賈從英;楊文洲;朱丹丹;;2008年淮安市首例輸入性瘧疾病例的調(diào)查報(bào)告[J];江蘇預(yù)防醫(yī)學(xué);2009年01期

10 王德強(qiáng);;大連口岸兩例輸入性瘧疾的調(diào)查分析[J];中國(guó)國(guó)境衛(wèi)生檢疫雜志;1992年05期

相關(guān)重要報(bào)紙文章 前3條

1 記者 劉澤林;海南嚴(yán)防輸入性瘧疾[N];健康報(bào);2013年

2 通訊員 魯加香 陳志勇 張大慶 記者 程守勤;江蘇寶應(yīng)輸入性瘧疾七年零死亡[N];健康報(bào);2013年

3 張明江　張珊珊 李峰;南通局妥善處置一起輸入性瘧疾[N];中國(guó)國(guó)門(mén)時(shí)報(bào);2007年

，

本文編號(hào)：1915985