本文關(guān)鍵詞：無(wú)菌動(dòng)物在腸-肝軸研究中的應(yīng)用前景　出處：《中國(guó)實(shí)驗(yàn)動(dòng)物學(xué)報(bào)》2017年06期 　論文類型：期刊論文

  更多相關(guān)文章： 無(wú)菌動(dòng)物 腸-肝軸 腸道菌群

【摘要】：腸道和肝之間通過(guò)腸-肝軸緊密相連,腸道疾病可以影響肝功能,肝疾病也可以誘發(fā)腸道菌群和功能的改變。無(wú)菌動(dòng)物是一種身體所有部位都沒(méi)有任何活的細(xì)菌、真菌、病毒及寄生蟲(chóng)的動(dòng)物,無(wú)菌動(dòng)物的出現(xiàn)為研究微生物與宿主之間的相互作用提供了有力的實(shí)驗(yàn)工具。同時(shí),由于無(wú)菌動(dòng)物缺乏正常腸道菌群的特點(diǎn),它在腸-肝軸的研究中也起到了極大的推進(jìn)作用。本文將對(duì)無(wú)菌動(dòng)物在腸-肝軸中的應(yīng)用前景做簡(jiǎn)要綜述。
[Abstract]:The intestine and liver are closely connected by the intestinal liver axis, and the intestinal diseases can affect the liver function, and the liver disease can also induce the change of intestinal flora and function. Aseptic animal is a kind of animal without any living bacteria, fungi, viruses and parasites. The emergence of sterile animals provides a powerful experimental tool for studying the interaction between microorganism and host. At the same time, because of the lack of normal intestinal flora, aseptic animals also play a great role in the study of the intestine - liver axis. This article will give a brief overview of the prospects for the application of aseptic animals in the intestine - liver axis.
【作者單位】： 浙江大學(xué)醫(yī)學(xué)院附屬第一醫(yī)院傳染病診治國(guó)家重點(diǎn)實(shí)驗(yàn)室感染性疾病診治協(xié)同創(chuàng)新中心;贛州市人民醫(yī)院;
【基金】：國(guó)家自然科學(xué)基金面上項(xiàng)目(No.81571953) 浙江省醫(yī)藥衛(wèi)生科技項(xiàng)目省部共建計(jì)劃(No.2015118507) 浙江省自然基金面上項(xiàng)目(No.LY16H190002)
【分類號(hào)】：R-332;R57
【正文快照】： diaohy@zju.edu.cn(1.State Key Laboratory for Diagnosis and Treatment of Infectious Diseases,Collaborative Innovation Center forDiagnosis and Treatment of Infectious Diseases,The First Affiliated Hospital,College of Medicine,ZhejiangUniversity,Hangzhou 31，

本文編號(hào)：1345399