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鯽魚(yú)對(duì)水中有機(jī)防曬劑的富集及代謝酶響應(yīng)

發(fā)布時(shí)間:2017-12-28 16:08

  本文關(guān)鍵詞:鯽魚(yú)對(duì)水中有機(jī)防曬劑的富集及代謝酶響應(yīng) 出處:《中國(guó)環(huán)境科學(xué)》2017年09期  論文類(lèi)型:期刊論文


  更多相關(guān)文章: 鯽魚(yú) OD-PABA 組織分布 生物富集 代謝酶


【摘要】:采用半靜態(tài)水體暴露方法研究了有機(jī)防曬劑對(duì)二甲氨基苯甲酸異辛酯(OD-PABA)在鯽魚(yú)不同組織的分布、累積及生態(tài)毒理效應(yīng).結(jié)果表明,OD-PABA在不同組織中的含量隨著水體暴露濃度的升高而持續(xù)升高,并在14或28d達(dá)到最大.不同濃度的OD-PABA在不同組織的生物富集因子(BCF)存在明顯差異,基于暴露14d和28d計(jì)算得到的BCF值,肝臟為123~186,皮膚為117~163,腎臟為90.2~147.OD-PABA對(duì)鯽魚(yú)肝臟EROD、PROD、BFCOD和GST活性都產(chǎn)生了誘導(dǎo)效應(yīng),其中EROD和GST的響應(yīng)更為顯著,最大誘導(dǎo)倍數(shù)分別為0.97和0.53倍.結(jié)果表明,水中的OD-PABA可在鯽魚(yú)體內(nèi)富集,并通過(guò)I相和II相代謝酶進(jìn)行生物轉(zhuǎn)化.
[Abstract]:The semi static water of organic sunscreen to two methyl amino benzoic acid isooctyl ester (OD-PABA) method to expose the distribution, accumulation and ecotoxicological effects in different tissues of crucian carp. The results showed that the content of OD-PABA in different tissues increased with the exposure concentration and water continued to rise, and reached a maximum at 14 or 28d. The concentration of OD-PABA in different tissues of the enrichment of biological factors (BCF) have obvious difference, the exposure of 14d and 28d were calculated based on the BCF value, liver 123~186, skin 117~163, kidney 90.2~147.OD-PABA on EROD, PROD and BFCOD in liver of crucian carp and GST activity induced effect, the response of EROD and GST more obviously, the maximum induction times were 0.97 and 0.53 times. The results show that the water OD-PABA in crucian carp enrichment, and through the I phase and II phase metabolic enzyme biological transformation.
【作者單位】: 西藏農(nóng)牧學(xué)院水利土木工程學(xué)院;河海大學(xué)環(huán)境學(xué)院淺水湖泊綜合治理與資源開(kāi)發(fā)教育部重點(diǎn)實(shí)驗(yàn)室;
【基金】:西藏農(nóng)牧學(xué)院雅江學(xué)者計(jì)劃(2015XYA01) 國(guó)家自然科學(xué)基金創(chuàng)新群體項(xiàng)目(51769034)
【分類(lèi)號(hào)】:X592
【正文快照】: 有機(jī)防曬劑(Organic UV Filters,OUVFs)是具有羰基共軛或雜環(huán)的芳香族有機(jī)化學(xué)品,具有強(qiáng)烈地選擇性吸收紫外線(xiàn)的性能.OUVFs除了作為防曬成分用于個(gè)人護(hù)理品以外,還被廣泛添加到家居產(chǎn)品、紡織品、塑料、光學(xué)產(chǎn)品、農(nóng)業(yè)化學(xué)品和涂料等產(chǎn)品中,防止紫外線(xiàn)照射[1].近年來(lái),紫外線(xiàn)輻

本文編號(hào):1346482

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