北京地區(qū)稀有血型庫的運行及臨床應(yīng)用研究
發(fā)布時間:2018-06-08 19:21
本文選題:稀有血型庫 + RhD陰性確認; 參考:《中國輸血雜志》2017年04期
【摘要】:目的了解北京市RhD陰性血使用及稀有血型篩選情況,更好地完善稀有血型庫,保障稀有血型患者的緊急用血問題。方法回顧性分析2009-2015年RhD陰性血使用及2014年1月-2016年7月RhD陰性確認、Duffy血型表現(xiàn)型、不規(guī)則抗體篩查及鑒定、Rh表現(xiàn)型檢測情況。結(jié)果 2009-2015年共向臨床醫(yī)院供應(yīng)RhD陰性全血4U,洗滌紅細胞11 U,懸浮紅細胞3 098 U,冰凍解凍去甘油紅細胞1 584 U,單采血小板223 U,新鮮冰凍血漿7 210 U;不同年份懸浮紅細胞與冰凍解凍去甘油紅細胞使用量差異有統(tǒng)計學(xué)意義(χ2=177.805,P0.05)。2014年1月-2016年7月檢驗科使用IgM抗-D試劑檢測RhD陰性的無償獻血者標本1 075份,RhD陰性確認試驗檢出Rh弱D型65例(6.05%),其中ccEe 31例(47.69%),CCee 13例(20.00%),Ccee 11例(19.62%)、Cc Ee 10例(15.38%);1 010例RhD陰性標本表型頻率以ccee 629例(62.28%)、Ccee 267例(26.44%)2種表型為主;617例RhD陰性標本Duffy血型表現(xiàn)型檢測Fy(a+b-)499例(80.88%),Fy(a+b+)99例(16.05%),Fy(a-b+)19例(3.08%)。結(jié)論采供血機構(gòu)應(yīng)制定RhD陰性懸浮紅細胞基礎(chǔ)庫存量,聯(lián)合冰凍解凍去甘油紅細胞為應(yīng)急保障的稀有血型供應(yīng)模式,并不斷增加稀有血型的篩選,完善稀有血型庫,以滿足稀有血型血液臨床需求。
[Abstract]:Objective to investigate the use of RhD negative blood and the screening of rare blood groups in Beijing, to improve the rare blood group bank and to protect the emergency blood use of rare blood group patients. Methods RhD negative blood use from 2009-2015 and RhD negative confirmation of Duffy blood group phenotype from January 2014 to July 2016 were analyzed retrospectively. Irregular antibody screening and identification were used to detect Rh phenotype. Results RhD negative whole blood 4U, washed red cell 11 U, suspended erythrocyte 3 098 U, frozen deglyceride red blood cell 1 584 U, single platelets 223 U, fresh frozen plasma 7 210 U were supplied to clinical hospitals from 2009 to 2015. There was significant difference in the use of deglycerol red blood cells between frozen and frozen thawed red blood cells (蠂 ~ 2 / 177.805) (蠂 ~ (2). From January 2014 to July 2016, the Rh weak D was detected by IgM anti-D reagent in 1 075 samples of RhD negative blood donors. 鍨,
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