本文選題：型糖尿病 + 血管回聲跟蹤技術(shù)　； 參考：《中華實(shí)用診斷與治療雜志》2017年01期

【摘要】：目的應(yīng)用血管回聲跟蹤技術(shù)檢測(cè)2型糖尿病患者足背動(dòng)脈及乆動(dòng)脈彈性指標(biāo),探討其與血脂及血糖的相關(guān)性。方法 2型糖尿病患者40例(觀察組),體檢健康者40例(對(duì)照組),檢測(cè)2組空腹血糖(fasting plasma glucose,FPG)、糖化血紅蛋白(glycosylated hemoglobin,HbA_(1c))、總膽固醇(total cholesterol,TC)、三酰甘油(triacylglycerol,TG)、高密度脂蛋白膽固醇(high density lipoprotein-cholesterol,HDL-C)、低密度脂蛋白膽固醇(low density lipoproteincholesterol,LDL-C)水平;應(yīng)用血管回聲跟蹤技術(shù)檢測(cè)2組足背動(dòng)脈、乆動(dòng)脈僵硬度(stiffness parameterβ,β)、血管壓力應(yīng)變彈性系數(shù)(pressure-strain elasticity coefficient,E_ρ)、順應(yīng)性(arterial compliance,AC)、脈搏波傳導(dǎo)速度(pulse wave velocityβ,PWVβ);Pearson相關(guān)分析2型糖尿病患者足背動(dòng)脈和乆動(dòng)脈彈性指標(biāo)與FPG、HbA_(1c)、TC、TG、HDL-C、LDL-C的相關(guān)性。結(jié)果觀察組FPG[(8.01±1.95)mmol/L]、HbA_(1c)[(8.66±1.64)mmol/L]、TC[(5.28±0.84)mmol/L]、TG[(1.96±0.89)mmol/L]、LDL-C[(3.11±0.65)mmol/L]高于對(duì)照組[(5.35±0.62)、(5.19±0.29)、(4.77±0.21)、(1.54±0.11)、(2.82±0.30)mmol/L](P0.05);觀察組左、右側(cè)足背動(dòng)脈β(14.41±5.06,14.68±4.80)、E_ρ[(198.35±72.89)、(199.82±67.24)kPa]、PWVβ[(8.46±1.66)、(8.52±1.51)m/s]高于對(duì)照組[(10.99±4.28)、(11.37±4.25);(137.09±52.38)、(141.27±54.82)kPa;(7.05±1.37)、(7.18±1.37)m/s](P0.05),AC值[(0.080±0.030)、(0.082±0.040)mm~2/kPa]低于對(duì)照組[(0.104±0.043)、(0.103±0.042)mm~2/kPa](P0.05);觀察組乆動(dòng)脈左、右側(cè)β(14.21±6.08、14.38±5.86)、E_ρ[(200.35±96.12)、(200.60±88.66)kPa]、PWVβ[(8.51±2.00)、(8.37±1.79)m/s]高于對(duì)照組[9.85±4.78、10.29±4.20;(122.77±63.00)、(127.15±52.10)kPa;(6.64±1.62)、(6.79±1.79)m/s](P0.05),AC值[(0.30±0.14)、(0.34±0.18)mm~2/kPa]低于對(duì)照組[(0.52±0.22)、(0.49±0.20)mm~2/kPa](P0.05);2型糖尿病患者足背動(dòng)脈、乆動(dòng)脈彈性指標(biāo)β、E_ρ、PWVβ與FPG、HbA_(1c)、TC、LDL-C呈正相關(guān),足背動(dòng)脈AC與FPG、TC呈負(fù)相關(guān),乆動(dòng)脈AC與HbA_(1c)、TC呈負(fù)相關(guān)。結(jié)論 2型糖尿病患者下肢動(dòng)脈粥樣硬化主要與FPG、HbA_(1c)、TC、LDL-C有關(guān),血管回聲跟蹤技術(shù)可快速、無(wú)創(chuàng)地檢查下肢小動(dòng)脈彈性,及時(shí)發(fā)現(xiàn)血管彈性功能受損情況。
[Abstract]:Objective to investigate the relationship between vascular echo tracking and blood lipids and blood glucose in patients with type 2 diabetes mellitus. Methods Forty patients with type 2 diabetes mellitus (observation group) and 40 healthy persons (control group) were examined for fasting plasma glucose GG, glycosylated hemoglobinated hemoglobin, total cholesterol, triacylglycerol TGG, high density lipoprotein cholesterol high density in the two groups of patients with type 2 diabetes mellitus (control group, n = 40), and glycosylated hemoglobinized hemoglobin (HbAG), total cholesterol (TC), triacylglycerol (TG), high density lipoprotein cholesterol (HDL-C) in the two groups. Low density protein cholesterol (LDL-C); Vascular echo tracking technique was used to detect the dorsal foot artery in two groups. Correlation between arterial stiffness and parameter 尾, pressure-strain elasticity coefficiency, compliance with arterial compliance, pulse wave velocity 尾 and pulse wave velocity in patients with type 2 diabetes mellitus 緇撴灉瑙傚療緇凢PG[(8.01鹵1.95)mmol/L],HbA_(1c)[(8.66鹵1.64)mmol/L],TC[(5.28鹵0.84)mmol/L],TG[(1.96鹵0.89)mmol/L],LDL-C[(3.11鹵0.65)mmol/L]楂樹(shù)簬瀵圭収緇刐(5.35鹵0.62),(5.19鹵0.29),(4.77鹵0.21),(1.54鹵0.11),(2.82鹵0.30)mmol/L](P0.05);瑙傚療緇勫乏,鍙充晶瓚寵儗鍔ㄨ剦尾(14.41鹵5.06,14.68鹵4.80),E_蟻[(198.35鹵72.89),(199.82鹵67.24)kPa],PWV尾[(8.46鹵1.66),(8.52鹵1.51)m/s]楂樹(shù)簬瀵圭収緇刐(10.99鹵4.28),(11.37鹵4.25);(137.09鹵52.38),(141.27鹵54.82)kPa;(7.05鹵1.37),(7.18鹵1.37)m/s](P0.05),AC鍊糩(0.080鹵0.030),(0.082鹵0.040)mm~2/kPa]浣庝簬瀵圭収緇刐(0.104鹵0.043),(0.103鹵0.042)mm~2/kPa](P0.05);瑙傚療緇勪箚鍔ㄨ剦宸，

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