本文選題：羥VD + 兒童��； 參考：《營(yíng)養(yǎng)學(xué)報(bào)》2017年01期

【摘要】：目的了解兒童血清25羥維生素D(25羥VD)水平的年齡及季節(jié)變化特點(diǎn),為更好實(shí)施VD(VD)缺乏癥防治方案奠定基礎(chǔ)。方法石家莊市夏季和冬季健康小兒692例,(男423,女269;夏季395;冬季297)年齡范圍0.1~14歲,分為嬰兒組、幼兒組,學(xué)齡前期,學(xué)齡期和青春期5個(gè)組。依采血月份,將對(duì)象分屬夏季(6、7、8月)和冬季(12、1、2月)。采集空腹靜脈血,酶聯(lián)免疫法測(cè)定25羥VD。結(jié)果 (1)男女孩血清25羥VD水平無(wú)統(tǒng)計(jì)學(xué)差異。(2)嬰兒期、幼兒期及學(xué)齡前期血清25羥VD夏季均高于冬季,差異有統(tǒng)計(jì)學(xué)意義;學(xué)齡期和青春期血清25羥VD夏季和冬季接近,差異無(wú)統(tǒng)計(jì)學(xué)意義。(3)夏、冬季,均為幼兒期血清25羥VD最高,嬰兒期次之,學(xué)齡前期呈現(xiàn)下降趨勢(shì);學(xué)齡期血清25羥VD較學(xué)齡前期繼續(xù)降低,青春期血清25羥VD達(dá)到最低。4、嬰兒期、幼兒期、學(xué)齡前期、學(xué)齡期和青春期夏季血清25羥VD≥50nmol/L比例分別為86%、90%、79%、42%和14%;冬季嬰兒期、幼兒期、學(xué)齡前期、學(xué)齡期和青春期血清25羥VD≥50nmol/L比例分別為66%、76%、45%、39%和17%。結(jié)論夏季嬰兒期、幼兒期、學(xué)齡前期具有良好VD營(yíng)養(yǎng)狀況。夏季各年齡段小兒,尤其是學(xué)齡期和青春期,曬太陽(yáng)(戶外活動(dòng))少時(shí),需要補(bǔ)充VD;在冬季,不但嬰兒期和幼兒期需要補(bǔ)充VD,學(xué)齡前期、學(xué)齡期和青春期也需補(bǔ)充VD。
[Abstract]:Objective to investigate the age and seasonal changes of serum 25 hydroxyvitamin D (VD) levels in children, and to lay a foundation for better implementation of VDX VD deficiency prevention programs. Methods 692 healthy children (male 423, female 269; summer 395; winter 297) in summer and winter in Shijiazhuang City were divided into infant group, preschool group, school age group and puberty group. According to the month of blood collection, the objects were divided into summer, July, August) and winter, 12, 1, February. Fasting venous blood was collected and 25 hydroxyVD was determined by enzyme-linked immunosorbent assay (Elisa). Results (1) there was no significant difference in serum 25-hydroxy-VD level between boys and girls. (2) in infancy, serum 25-hydroxyVD in infants and pre-school children was higher in summer than in winter, the difference was statistically significant, and the serum 25-hydroxy-VD levels in school age and adolescence were similar in summer and winter. The difference was not statistically significant in summer. In winter, the serum 25-hydroxy-VD was the highest in early childhood, followed by infancy, and decreased in pre-school, and the 25-hydroxy-VD in school-age was lower than that in pre-school. The ratio of serum 25 hydroxyVD 鈮，

本文編號(hào)：1889214