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內耳前庭內淋巴體積測量在梅尼埃病中的應用研究

發(fā)布時間:2018-05-06 08:15

  本文選題:梅尼埃病 + 前庭內淋巴 ; 參考:《廣西醫(yī)科大學》2017年碩士論文


【摘要】:目的:探討內耳前庭內淋巴體積測量在梅尼埃病中的應用價值。方法:20例經臨床確診的梅尼埃病患者經鼓膜穿刺雙側鼓室內注入釓噴酸葡胺稀釋液,24h后行MRI掃描,對內耳前庭內淋巴體積進行測量。10例為術前患者,其中7例為單側發(fā)病患者,3例為雙側發(fā)病患者;10例為行單側半規(guī)管填塞術后患者,其中8例為單側發(fā)病患者,2例為雙側發(fā)病患者。采用配對t檢驗比較單側發(fā)病術前患者患側耳與健側耳內耳前庭內淋巴體積、單側發(fā)病術后患者術后耳與健側耳內耳前庭內淋巴體積的差異;采用獨立樣本t檢驗比較術前患者患側耳與術后患者術后耳內耳前庭內淋巴體積的差異。結果:7例單側發(fā)病術前患者患側耳和健側耳內耳前庭內淋巴體積測量值分別為(11.67±3.63)mm3、(7.99±2.69)mm3,8例單側發(fā)病術后患者術后耳和健側耳內耳前庭內淋巴體積測量值分別為(7.54±2.55)mm3、(7.41±2.00)mm3,10例術前患者患側耳與10例術后患者術后耳內耳前庭內淋巴體積測量值分別為(10.93±3.14)mm3、(7.46±2.26)mm3;單側發(fā)病術前患者患側耳和健側耳內耳前庭內淋巴體積、術前患者患側耳與術后患者術后耳內耳前庭內淋巴體積差異有統(tǒng)計學意義(P值0.05);單側發(fā)病術后患者術后耳與健側耳內耳前庭內淋巴體積差異無統(tǒng)計學意義(P值0.05)。結論:內耳前庭內淋巴體積測量能為臨床診斷梅尼埃病提供影像學依據,同時為梅尼埃病的療效評估提供有用的信息。
[Abstract]:Objective: to evaluate the value of intravestibular lymphatic volume measurement in Meniere's disease. Methods Twenty patients with Meniere's disease diagnosed by clinical diagnosis were treated with MRI scan after 24 hours of injection of meglumine gadolinium poumate diluted solution into the tympanic chamber through tympanic membrane puncture. The volume of the vestibular lymph nodes in the inner ear was measured in 10 patients before operation. Among them, 7 cases were unilateral, 3 cases were bilateral, 10 cases were treated with unilateral semicircular canal tamponade, 8 cases were unilateral and 2 cases were bilateral. T test was used to compare the volume of the vestibular lymphatic volume between the patients with unilateral preoperation and that of the patients with unilateral preoperation, and the volume of the vestibular lymphatic volume between the patients after unilateral onset and that of the patients after unilateral operation. T test was used to compare the volume of vestibular lymphoid volume between preoperatively and postoperatively patients with auricular vestibule. Results the volume measurements of the vestibular lymphatic volume in 7 cases of unilateral preoperation and 7 cases of healthy inner ear were 11.67 鹵3.63 mm ~ (3), 7.99 鹵2.69 mm ~ (3) and 7.54 鹵2.55 mm ~ (3) and 7.41 鹵2.00 mm ~ (3) ~ (-1), respectively, before and after operation of unilateral and internal ear of healthy lateral ear were 7.54 鹵2.55 mm ~ (3) and 7.41 鹵2.00 mm ~ (-1), respectively. The volume of vestibular lymphoid volume was 10.93 鹵3.14 mm ~ (3) and 7.46 鹵2.26 mm ~ (3) respectively in the patients with and 10 cases after operation, and the volume of the vestibular lymphoid volume of the affected and healthy ears was 7.46 鹵2.26 mm ~ (3), respectively. There was significant difference in the volume of vestibular lymphatic volume between preoperation and postoperative patients, but there was no significant difference in the volume of vestibular lymph between unilateral and healthy ears. Conclusion: the measurement of intravestibular lymphatic volume of inner ear can provide imaging basis for clinical diagnosis of Meniere's disease and provide useful information for the evaluation of curative effect of Meniere's disease.
【學位授予單位】:廣西醫(yī)科大學
【學位級別】:碩士
【學位授予年份】:2017
【分類號】:R764.33;R445.2

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