黏液型銅綠假單胞菌臨床分布與耐藥性分析
發(fā)布時間:2018-04-15 11:39
本文選題:黏液型銅綠假單胞菌 + 臨床分布。 參考:《中華醫(yī)院感染學(xué)雜志》2017年12期
【摘要】:目的為臨床合理使用抗菌藥物治療黏液型銅綠假單胞菌感染提供必要的病原學(xué)依據(jù)。方法收集醫(yī)院2012年1月-2016年12月臨床分離的86株黏液型銅綠假單胞菌感染病例,通過查閱病歷獲得患者一般資料、疾病情況、抗菌藥物使用等信息,回顧性分析黏液型銅綠假單胞菌的臨床分布、耐藥性及療效。結(jié)果臨床送檢標(biāo)本共分離出黏液型銅綠假單胞菌86株,男性占72.09%,女性占27.01%;老年人占83.72%,中年人占12.79%,青年人占3.49%;肺部感染、泌尿系感染和創(chuàng)傷感染分別占93.02%、3.49%和3.49%;氨芐西林/舒巴坦和磺胺甲VA唑/甲氧芐啶的耐藥率為98.84%、95.35%,替卡西林和替卡西林/克拉維酸的耐藥率為22.09%、13.95%,哌拉西林和哌拉西林/他唑巴坦的耐藥率為11.63%和10.47%;療效顯著的病例占83.72%。結(jié)論黏液型銅綠假單胞菌感染主要集中在老年男性的呼吸道感染,臨床應(yīng)根據(jù)藥敏結(jié)果合理選用抗菌藥物。
[Abstract]:Objective to provide necessary etiological evidence for the rational use of antimicrobial agents in the treatment of myxomonas aeruginosa infection.Methods 86 clinical isolates of Pseudomonas aeruginosa from January 2012 to December 2016 were collected, and the general information of patients, the condition of disease and the use of antimicrobial agents were obtained by consulting the medical records.The clinical distribution, drug resistance and efficacy of mucinous Pseudomonas aeruginosa were analyzed retrospectively.Results A total of 86 strains of Pseudomonas aeruginosa were isolated from clinical samples, including 72.09 males and 27.01 females, 83.72% of the elderly, 12.79% of the middle-aged, 3.49% of the young, pulmonary infection.Urinary tract infection and trauma infection accounted for 93.02% and 3.49% respectively, ampicillin / sulbactam and sulfamethoxazole / trimethoprim were 98.84 and 95.355.The resistant rates of tekassim and ticacillin / clavulanic acid were 22.0913.95, piperacillin and piperacillin were higher than those of ampicillin / sulbactam and sulfamethoxazole / trimethoprim.The drug resistance rate of tazobactam was 11.63% and 10.47%, and 83.72% of the patients had significant curative effect.Conclusion Myxomonas aeruginosa infection is mainly concentrated in the respiratory tract infection of the aged men, and antibiotics should be selected reasonably according to the results of drug sensitivity.
【作者單位】: 重慶醫(yī)科大學(xué)附屬大學(xué)城醫(yī)院檢驗科;
【分類號】:R446.5
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