本文關(guān)鍵詞： 晚期腎病 血液透析 免疫系統(tǒng) 免疫系統(tǒng)刺激物 免疫紊亂　出處：《現(xiàn)代預(yù)防醫(yī)學(xué)》2017年09期 　論文類型：期刊論文

【摘要】：透析后腎組織發(fā)生慢性炎癥是血液透析后的一種常見副作用,嚴(yán)重時會導(dǎo)致進展性晚期腎病,危及患者生命。在免疫學(xué)上,血液透析引起腎組織出現(xiàn)慢性炎癥的原因是血透患者的免疫系統(tǒng)發(fā)生紊亂,其危險因素包括尿毒癥毒素和透析相關(guān)因子等免疫系統(tǒng)刺激物。在免疫系統(tǒng)刺激物的長期刺激作用下,免疫系統(tǒng)紊亂主要表現(xiàn)在補體紊亂、先天性免疫紊亂和獲得性免疫紊亂。目前國內(nèi)外在血液透析患者免疫系統(tǒng)紊亂方面有很多新的研究,但國內(nèi)沒有綜述,故本文將從免疫系統(tǒng)刺激物、補體系統(tǒng)紊亂、先天性免疫系統(tǒng)紊亂和獲得性免疫系統(tǒng)紊亂等方面的發(fā)病機理進行闡述,為預(yù)防和治療血液透析所引起的腎組織慢性炎癥提供理論基礎(chǔ)。
[Abstract]:Chronic inflammation of renal tissue after dialysis is a common side effect after hemodialysis. In immunology, it can lead to advanced advanced nephropathy and endanger the life of patients. The cause of chronic inflammation in renal tissue caused by hemodialysis is the disorder of the immune system of hemodialysis patients. The risk factors include immune system irritants such as uremic toxins and dialysation-related factors. Congenital immune disorders and acquired immune disorders. At present, there are many new studies on immune system disorders in hemodialysis patients at home and abroad, but there is no review in China, so this article will focus on immune system irritants, complement system disorders, The pathogenesis of congenital immune system disorder and acquired immune system disorder is expounded to provide a theoretical basis for the prevention and treatment of chronic inflammation of renal tissue caused by hemodialysis.
【作者單位】： 廣州市紅十字會醫(yī)院;
【分類號】：R692.5
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本文編號：1515908