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面向腦狀態(tài)監(jiān)測的腦電與腦氧信號采集系統(tǒng)

發(fā)布時間:2018-01-12 23:27

  本文關(guān)鍵詞:面向腦狀態(tài)監(jiān)測的腦電與腦氧信號采集系統(tǒng) 出處:《浙江大學(xué)》2017年碩士論文 論文類型:學(xué)位論文


  更多相關(guān)文章: 腦電 腦功能監(jiān)護 組織血氧飽和度 近紅外光譜技術(shù) ADS1299


【摘要】:大腦是人體最重要的部位,幾乎人體所有的活動都與大腦有密切相關(guān)的聯(lián)系。對大腦健康狀態(tài)的檢測一直是人們研究的重點,現(xiàn)如今有許多檢測技術(shù)可應(yīng)用于大腦相關(guān)疾病的檢測。其中腦電圖(EEG)和近紅外光譜技術(shù)(NIRS)具有良好的時間分辨率,已經(jīng)被廣泛的應(yīng)用于大腦健康狀態(tài)監(jiān)護領(lǐng)域。腦電是由大腦神經(jīng)活動的電信號產(chǎn)生的,可以反映大腦神經(jīng)活動和相關(guān)代謝信息,而近紅外光譜技術(shù)(NIRS)可以檢測組織的血液相關(guān)參數(shù),可以對大腦的血液活動或代謝狀態(tài)進行有效評估。采用兩種檢測技術(shù)共同對大腦健康狀態(tài)信息進行檢測,將腦電圖與血液相關(guān)參數(shù)所包含的信息相結(jié)合,可以完成對大腦健康更加全面的監(jiān)護。本文基于腦電圖和近紅外光譜檢測技術(shù),完成腦電和腦氧信號采集系統(tǒng)的初步研發(fā),采用雙通道腦電和單通道腦氧信號的采集的方案,檢測的部位主要是人腦前額腦區(qū)部位。本文首先介紹了大腦狀態(tài)檢測技術(shù)的研究現(xiàn)狀和發(fā)展,特別是近年來出現(xiàn)的多種腦狀態(tài)檢測技術(shù)相結(jié)合的研究。然后介紹了腦電信號檢測技術(shù)和近紅外光譜技術(shù)的基本原理,并對系統(tǒng)的采集方案和校準(zhǔn)原理加以說明。腦電信號采集模塊是基于TI公司的ADS1299進行設(shè)計的,在ADS1299前端加入濾波電路和保護電路等預(yù)處理電路以保證電路的安全。腦氧信號采集模塊采用雙波長、雙光電探測器的設(shè)計方案,采用LED發(fā)光二極管作為光源,采用微處理器STM32對腦氧信號進行采樣并控制LED驅(qū)動電路調(diào)節(jié)電流大小。本文對系統(tǒng)進行了性能測試和系統(tǒng)參數(shù)的測量,采用標(biāo)準(zhǔn)腦電信號作為信號源對腦電采集系統(tǒng)的性能進行了驗證,采用積分球原理對腦氧采集系統(tǒng)進行了校準(zhǔn)實驗,并對人體進行實際測量實驗。系統(tǒng)的實驗結(jié)果達到了較好的效果,初步確定此系統(tǒng)的可靠性和實用性。
[Abstract]:The brain is the most important part of the human body, almost all human activities are closely related to the brain. The detection of brain health status has been the focus of research. Nowadays, many detection techniques can be used in the detection of brain related diseases. Among them, electroencephalogram (EEG) and near infrared spectroscopy (NIR) have good time resolution. It has been widely used in the field of brain health monitoring. EEG is generated by electrical signals of brain nerve activity, which can reflect the brain nerve activity and related metabolic information. Near infrared spectroscopy (NIR) can be used to detect the blood parameters of tissues. It can effectively evaluate the blood activity or metabolic state of the brain. Two kinds of detection techniques are used to detect the information of the brain health state together, and the EEG is combined with the information contained in the blood related parameters. This paper based on EEG and near infrared spectrum detection technology to complete EEG and EEG and EEG signal acquisition system preliminary development. This paper introduces the research status and development of brain state detection technology, which is mainly located in the prefrontal region of human brain by the method of two channel EEG and single channel cerebral oxygen signal acquisition. Especially in recent years a variety of brain state detection technology combined research. Then the basic principles of EEG detection technology and near-infrared spectroscopy technology are introduced. The acquisition scheme and calibration principle of the system are explained. The EEG acquisition module is designed based on TI's ADS1299. Pre-processing circuits such as filter circuit and protection circuit are added to the front end of ADS1299 to ensure the safety of the circuit. The design of dual-wavelength and dual-photodetector is used in the module of cerebral oxygen signal acquisition. The LED light-emitting diode is used as the light source. The microprocessor STM32 is used to sample the cerebral oxygen signal and to control the current size of the LED drive circuit. The performance of the system and the measurement of the system parameters are tested in this paper. The performance of the EEG acquisition system is verified by using the standard EEG signal as the signal source, and the calibration experiment of the EEG acquisition system is carried out by using the integral sphere principle. The experimental results of the system are satisfactory, and the reliability and practicability of the system are preliminarily determined.
【學(xué)位授予單位】:浙江大學(xué)
【學(xué)位級別】:碩士
【學(xué)位授予年份】:2017
【分類號】:TP274.2;R318

【參考文獻】

相關(guān)期刊論文 前2條

1 鄭毅;駱清銘;劉謙;李婷;張中興;龔輝;;適于腦功能活動檢測的便攜式近紅外光譜儀的研制[J];中國生物醫(yī)學(xué)工程學(xué)報;2007年06期

2 黃力宇,程敬之;腦電圖在全身麻醉深度監(jiān)測中的應(yīng)用[J];國外醫(yī)學(xué).生物醫(yī)學(xué)工程分冊;2000年05期



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