本文關(guān)鍵詞： 功能性研究 syndromic 人類染色體 heterogeneity 易感位點 劉歡 Genome cleft 美國愛荷華大學(xué) 基因突變 　出處：《口腔醫(yī)學(xué)研究》2017年08期 　論文類型：期刊論文

【摘要】：正武漢大學(xué)口腔醫(yī)院選派到美國愛荷華大學(xué)(University of Iowa)的博士后劉歡醫(yī)師對唇腭裂GWAS研究功能性解析取得進展,成果以"Identification of common non-coding variants at 1p22that are functional for non-syndromic orofacial clefting"(《非綜合征型唇腭裂位于人類染色體1p22區(qū)段功能性致病常見突變鑒定》)為題,于2017年3月13日在Nature Communications(自然通訊)雜志在線發(fā)表。這是我院研究人員繼邊專教授團隊于上月在Nature Communications(自然通訊)發(fā)表"Genome-wide analyses of non-syndromic cleft lip with palate identify fourteen novel loci and genetic heterogeneity"《非綜合征型唇腭裂全基因組關(guān)聯(lián)分析發(fā)現(xiàn)了14個新的易感位點和遺傳異質(zhì)性》)之后,在唇腭裂研究領(lǐng)域取得的又一重要進展。
[Abstract]:Dr. Liu Huan, a postdoctoral candidate from the Stomatology Hospital of Wuhan University, has made progress in functional analysis of cleft lip and palate GWAS. The results were based on "Identification of common non-coding variants at 1p22 that are functional for non-syndromic orofacial clefting". Published online on March 13th 2017 in the journal Nature communications. This is the publication of "Genome-wide analyses of non-syndromic cleft lip with palate identify fourteen novel loci and genetic heterogeneity" in Nature Communications last month by a team of researchers from our hospital. The whole genome association analysis of cleft lip and palate revealed 14 new susceptibility loci and genetic heterogeneity. Another important progress has been made in the field of cleft lip and palate.
【分類號】：R782.2
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本文編號：1550380