目的:鋅具有良好的降解性能和生物相容性,被視為一種很有前途的骨修復(fù)材料。然而,鋅金屬作為骨植入物時的力學(xué)強(qiáng)度難以滿足承重骨修復(fù)的需求,并存在炎癥反應(yīng)的風(fēng)險。本文旨在探討稀土釹合金化對鋅骨植入物激光成形質(zhì)量的影響,為改善鋅合金的成形質(zhì)量、提高力學(xué)性能及增加抗炎活性提供理論依據(jù)。創(chuàng)新點:1.在增材制造過程中,添加釹能夠有效改善鋅基合金的成形質(zhì)量;2.稀土釹提高了鋅基合金的力學(xué)性能,同時也賦予了抗炎活性。方法:1.通過實驗對比鋅釹合金的表面形貌,計算出相應(yīng)的致密度,并分析釹對鋅基合金成形質(zhì)量的影響（圖2）;2.基于不同實驗對比鋅釹合金的微觀組織結(jié)構(gòu)及力學(xué)強(qiáng)度的變化,并探討稀土釹提高力學(xué)性能的原因（圖3～5和表1）;3.通過電化學(xué)實驗和浸泡實驗,分析稀土釹對降解性能的影響（圖6和7）;4.基于體外生物學(xué)實驗,對比分析釹對抗炎活性和細(xì)胞活性的影響（圖8和9）。結(jié)論:1.稀土釹提高了激光增材制造鋅合金的成形質(zhì)量,并使其致密化率高達(dá)98.71%;2.釹合金化有助于晶粒細(xì)化和第二相強(qiáng)化,使極限抗拉強(qiáng)度提高到了（119.3±5.1） MPa;3.釹合金化能抑制促炎因子的釋放,促進(jìn)抗炎因子的釋放,進(jìn)而使鋅... 

【文章頁數(shù)】：16 頁

【文章目錄】：
1 Introduction
2 Materials and methods
    2.1 Material and sample fabrication
    2.2 Microstructural characterization
    2.3 Mechanical tests
    2.4 Electrochemical and immersion experiments
    2.5 Evaluation of anti-inflammatory activity
    2.6 Cytotoxicity assay
    2.7 Statistical analysis
3 Results
    3.1 Formation quality and microstructure evolution
    3.2 Mechanical properties
    3.3 Corrosion behavior
    3.4 Anti-inflammatory properties
    3.5 Cytotoxicity
4 Discussion
    4.1 Forming quality and microstructural features
    4.2 Influence of alloying treatment on mechanical properties
    4.3 Corrosion behavior and anti-inflammatory activity of Zn–Nd alloy
5 Conclusions


【參考文獻(xiàn)】：
期刊論文
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