本文選題：頻域近紅外光譜法 + 生物組織��； 參考：《光譜學與光譜分析》2017年04期

【摘要】：基于光子在生物組織中的輻射傳輸理論以及Feng模型,應用頻域近紅外光譜法研究生物組織中異質(zhì)體位置的變化,對出射光的光強和相位變化的影響及規(guī)律。設計了一仿真實驗,用牛奶代替強散射性質(zhì)的生物組織,并在牛奶中放置一個高度可控的具有一定吸收系數(shù)和散射系數(shù)的小球。移動小球在牛奶中的高度,檢測出射光的交流幅度AC、直流光強DC和相位延遲Phase的值,繪制小球位于不同深度時AC,DC和Phase的曲線,并探討其變化規(guī)律。結果表明,隨著小球在牛奶中深度的變化,光強AC,DC和相位Phase呈現(xiàn)一定的相關性;隨著光源和檢測器之間距離的增加,檢測到的光強和相位曲線的波谷點均向右偏移;當小球偏離光源和檢測器越遠,對檢測到的光強和相位的影響越小。驗證了光子在生物組織中的傳輸規(guī)律,為用頻域近紅外光譜法進行組織光學參數(shù)的檢測及組織中異質(zhì)體位置的定位奠定了基礎。
[Abstract]:Based on the radiation transfer theory of photons in biological tissues and Feng model, the change of heterogeneity position in biological tissues is studied by using the frequency domain near infrared spectroscopy (NIR) method, and the influence and regularity of the light intensity and phase change on the light intensity and phase of the emitted light are studied. A simulation experiment was designed in which milk was used to replace the biological tissue with strong scattering properties and a highly controllable small ball with certain absorption and scattering coefficients was placed in the milk. By moving the height of the ball in milk, the AC amplitude, DC intensity DC and phase delay phase were detected, and the curves of AC DC and phase were drawn when the ball was located at different depths, and the variation of AC DC and phase was discussed. The results show that with the change of the depth of the ball in milk, there is a certain correlation between the light intensity ACDC and the phase, and with the increase of the distance between the light source and the detector, the detected light intensity and the wave valley point of the phase curve are all shifted to the right. When the sphere deviates from the light source and detector, the effect on the detected intensity and phase is smaller. The transmission of photons in biological tissues is verified, which lays a foundation for the detection of optical parameters of tissues and the location of heterogeneity in tissues by frequency domain near infrared spectroscopy (NIR).
【作者單位】： 中國農(nóng)業(yè)大學信息與電氣工程學院;教育部現(xiàn)代精細農(nóng)業(yè)系統(tǒng)集成研究重點實驗室;食品質(zhì)量與安全北京實驗室;
【基金】：國家自然科學基金項目(31101289)資助
【分類號】：Q6-3;O657.33

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