本文選題：冬蟲夏草 + 甘露醇��； 參考：《光譜學與光譜分析》2016年04期

【摘要】：用飛行時間二次離子質(zhì)譜(TOF-SIMS)分析研究了冬蟲夏草中兩個最重要的藥效活性物質(zhì),甘露醇和蟲草素,重點研究對應質(zhì)量數(shù)251amu的質(zhì)譜峰含有的化學信息。利用TOF-SIMS高質(zhì)量分辨率的優(yōu)勢,檢測并識別251和252amu質(zhì)譜峰的信號有可能不是保健藥理活性物質(zhì)蟲草素C_(10)H_(13)N_5O_3(251amu)產(chǎn)生的分子離子峰M~+,[M+H]~+,這或許就是文獻中有關研究蟲草素存在爭論的原因。TOF-SIMS分析結(jié)果為進一步解讀251amu質(zhì)譜峰的化學內(nèi)含、深入研究冬蟲夏草中蟲草素提供了依據(jù);同時就甘露醇對應的(181amu附近)TOF-SIMS負離子質(zhì)譜峰做了細致的解讀,確認181amu質(zhì)譜峰是識別冬蟲夏草中甘露醇的可靠依據(jù)。本研究證明,TOF-SIMS是分析、研究、鑒別冬蟲夏草的有效手段。
[Abstract]:Two of the most important active substances in Cordyceps sinensis, mannitol and cordycepin, were analyzed by TOF-SIMS, and the chemical information of mass spectrum peak corresponding to mass number 251amu was studied. Taking advantage of the high quality resolution of TOF-Sims, it is possible to detect and identify the signals of 251-and 252amu mass spectrum peaks that are not the molecular ion peaks M ~, [M H] ~, produced by Cordycepin C _ (10) H _ (10) H ~ (13) N _ (5) O _ (3) O _ (5) O _ (5) ~ (?) The results of TOF-Sims analysis may provide a basis for further understanding the chemical content of 251amu mass peak and further studying Cordycepin in Cordyceps sinensis. At the same time, the peak of TOF-Sims negative ion mass spectrum corresponding to mannitol near 181amu was interpreted in detail, and it was confirmed that the peak of 181amu mass spectrometry was a reliable basis for identifying mannitol in Cordyceps sinensis (Cordyceps sinensis). This study proved that TOF Sims is an effective means to analyze, study and identify Cordyceps sinensis.
【作者單位】： 清華大學分析中心;ULVAC-PHI
【基金】：國家自然科學基金項目(30870262)資助
【分類號】：R284.1;O657.63
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本文編號：1995702