幾種新型固態(tài)抗菌材料的制備
[Abstract]:Microbes exist in every corner of life and affect our lives in one way or another. Some of them are indispensable to maintaining the ecological environment, while others pose a serious threat to people's lives and health. In order to survive, people have to use all kinds of methods to resist the erosion of health by microorganisms. Antibiotics are an important weapon for people to resist pathogenic microorganisms, but the drug resistance of bacteria has become an increasingly serious problem. The speed of new drug development is far from keeping pace with the drug resistance of bacteria. In addition to reasonably standardizing the use of drugs and adhering to healthy living habits, it is necessary to solve this problem. It is necessary to fundamentally reduce the chance of human contact with pathogenic microorganisms-the wide use of cheap and efficient disinfectants is inevitable, in view of the strong irritation of most disinfectants, in some cases where disinfectants are not suitable for use, It is necessary to use mild, lasting and efficient polymer antibacterial coating on the surface of public fitness leisure and entertainment equipment. In this paper, polymer quaternary ammonium salt and polymyxin were seeded on two different medium. one kind of matrix was a very stable Amphiphilic yeast carbon slag ball obtained by hydrothermal reaction using waste beer yeast as raw material. The other matrix is nanometer iron tetroxide microspheres synthesized by hydrothermal reaction, on the basis of which 4-vinylpyridine is further grafting by distillation precipitation method. Two different halides were used in the mixed solvent to form salt with poly4-vinylpyridine. Polymyxin was modified on the surface of carbon slag microspheres with EDC,NHS as activating agent. Ma Erwen laser particle size meter, Fourier transform infrared spectrometer, scanning and transmission electron microscope were used. The chemical composition and micromorphology of carbon slag microspheres and iron tetroxide microspheres before and after modification were detected and analyzed by thermogravimetric analyzer and other instruments. The content of polymyxin on the surface of carbon slag microspheres was determined by high efficiency liquid, and the charge number on the surface of poly4-vinylpyridine modified microspheres was determined by ultraviolet spectrophotometry. Escherichia coli and Staphylococcus aureus were used as experimental strains and distilled water as dispersion medium to simulate the natural water environment, and the antibacterial activity of the materials was determined.
【學(xué)位授予單位】:河南大學(xué)
【學(xué)位級(jí)別】:碩士
【學(xué)位授予年份】:2015
【分類號(hào)】:TB34
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