胰腺癌患者根治性切除術(shù)后腹腔感染的病原菌分析研究
[Abstract]:Objective to investigate the distribution and drug resistance of pathogenic bacteria in abdominal infection after radical resection of pancreatic cancer, and to provide evidence for clinical treatment. Methods the clinical data of 318 patients with pancreatic cancer undergoing radical resection from January 2009 to December 2013 in PLA General Hospital were analyzed retrospectively, and the etiological characteristics and drug resistance of postoperative abdominal infection were analyzed by SPSS 13.0 software. Results 42 cases of abdominal infection occurred after operation, the infection rate was 13.2%, 76 strains of pathogenic bacteria were isolated from drainage solution, including Gram-negative bacteria (57.9%), Gram-positive bacteria (35.5%) and fungi (6.6%). Pseudomonas aeruginosa, Escherichia coli and Klebsiella pneumoniae were sensitive to imipenem, the resistance rates were 7.7%, 0% and 8.3%, respectively. Enterococcus faecium and Staphylococcus aureus were sensitive to teicoplanin and vancomycin, and the resistance rates were 9.1%, 9.1% and 10.0%, respectively. Conclusion Peritoneal infection is a common complications after radical resection of pancreatic cancer. Reducing intraoperative pollution and unobstructed drainage after operation is an effective measure to prevent pancreatic cancer. According to the results of drainage culture, the application of reasonable antibiotics is the key to its treatment.
【作者單位】: 臨沂市沂水中心醫(yī)院普外二科;解放軍總醫(yī)院肝膽外科;
【基金】:全軍醫(yī)學(xué)科研“十二五”基金資助項(xiàng)目(CWS11J096)
【分類號(hào)】:R446.5
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