武漢大學人民醫(yī)院多重耐藥的病原菌分布及耐藥特點
[Abstract]:Objective to investigate the distribution characteristics and drug resistance of multidrug resistant bacteria in hospitalized patients of people's Hospital of Wuhan University, and to provide laboratory basis for multidrug resistant bacteria control measures and rational use of clinical antibiotics in hospital departments. Methods the target surveillance data of multidrug resistant bacteria in our hospital from September 2014 to September 2015 were analyzed retrospectively. WHONET 5.6 and Excel were used for statistical analysis. Results A total of 7 391 strains of pathogenic bacteria and 1 548 strains of multidrug resistant bacteria were isolated and identified. The detection rate was 20.94, including Acinetobacter baumannii (28.81%), Escherichia coli (24.61%), Pseudomonas aeruginosa (14.53%), Klebsiella pneumoniae (12.79%) and MRSA (12.22%). There were 1 006 strains (64.99%) in respiratory and neurology departments, and 52.95% in sputum and 16.69% in urine. The resistance rate of Acinetobacter baumannii to cefoperazone / sulbactam was 71.4, and to other antibiotics was higher than 86.7; Escherichia coli to levofloxacin 53.6 and amikacin to 3.0; Pseudomonas aeruginosa to amitrotrix. The resistance rate of Klebsiella pneumoniae to piperacillin / tazobactam was 12.3%, Staphylococcus aureus to penicillin, The resistant rates of erythromycin and clindamycin were 96. 5% and 60. 0%, respectively. No vancomycin and teicoplanin resistant Staphylococcus aureus were found, and 13 strains of Enterococcus were found to be resistant to vancomycin. Conclusion multidrug resistant bacteria are the main pathogens of nosocomial infection. General hospitals should take the initiative to prevent and control antibiotics and strengthen the management and rational use of antibiotics.
【作者單位】: 武漢大學人民醫(yī)院檢驗科;
【基金】:國家臨床重點?(財社2010305)
【分類號】:R446.5
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