發(fā)布時間：2018-01-11 14:36

  本文關鍵詞：燒傷科中心靜脈導管相關感染病原菌分布及耐藥分析　出處：《中國病原生物學雜志》2016年01期 　論文類型：期刊論文

  更多相關文章： 中心靜脈導管 相關因素 病原菌 耐藥

【摘要】：目的探討中心靜脈導管技術在燒傷科應用過程中造成感染的因素、病原菌分布和耐藥情況,為燒傷科臨床中心靜脈導管感染預防和治療提供依據(jù)。方法選取2011年1月-2014年12月燒傷科就診住院并行中心靜脈導管患者1 326例資料,98例出現(xiàn)中心靜脈導管相關感染。抽取外周靜脈血及導管內(nèi)血進行培養(yǎng),鑒定菌株并進行藥敏試驗。結(jié)果 1 326例中心靜脈導管治療患者中98例感染,感染率7.39%。其中男性感染率7.33%(71/969),女性感染率7.56%(21/357)。年齡50歲、≥50歲者感染率分別為5.77%(42/728)和9.36%(56/598);穿刺部位為鎖骨下靜脈者、穿刺頸內(nèi)靜脈者和穿刺股靜脈者感染率分別為7.03%(43/612)、7.18%(37/515)和9.05%(18/199);導管留置時間20d、≥20d者感染率分別為5.60%(46/821)和10.30%(52/505);住院時間45d、≥45d者感染率分別為4.98%(38/763)和9.05%(60/663);各組間感染率差異均有統(tǒng)計學意義(χ2年齡=6.200,χ2穿刺部位=4.5210,χ2留置時間=10.0661,χ2住院時間=9.1791,P均0.05)。分離出103株病原菌,其中革蘭陰性菌48株(占46.60%),革蘭陽性菌44株(占42.72%),真菌19株(占18.45%)。金黃色葡萄球菌檢出最多,共21株(占20.39%),其次為銅綠假單胞菌(18株)。銅綠假單胞菌對青霉素、慶大霉素耐藥率分別為66.67%和61.11%,未發(fā)現(xiàn)亞胺培南耐藥株;大腸埃希菌和金黃色葡萄球菌對青霉素、慶大霉素、美羅培南和亞胺培南耐藥率分別為62.50%、62.50%、11.11%、11.11%和71.43%、61.90%、4.76%、4.76%;未發(fā)現(xiàn)耐萬古霉素金黃色葡萄球菌。討論患者年齡、穿刺部位、留置時間和住院時間與中心靜脈導管引發(fā)血流感染密切相關,分離病原菌以革蘭陽性和革蘭陰性桿菌為主,臨床用藥要參考藥敏結(jié)果,以避免耐藥菌株產(chǎn)生。
[Abstract]:Objective to investigate the factors causing infection, the distribution of pathogenic bacteria and drug resistance during the application of central venous catheter technique in burn department. Methods 1 326 inpatients with central venous catheter from January 2011 to December 2014 were selected for the prevention and treatment of central venous catheter infection in burn department. 98 cases were infected with central venous catheter. Peripheral and intraductal blood were collected for culture. Results among the 1 326 patients treated with central venous catheter, 98 cases were infected, the infection rate was 7.39%, and the male infection rate was 7.33% 969%. The female infection rate was 7.56 / 3570.The infection rate was 5.7742 / 728 for those aged 50 years and 鈮，

本文編號：1409961