發(fā)布時(shí)間：2018-01-04 06:27

  本文關(guān)鍵詞：微電子肌電橋關(guān)鍵電路的研究和設(shè)計(jì)　出處：《東南大學(xué)》2015年碩士論文　論文類型：學(xué)位論文

  更多相關(guān)文章： 微電子肌電橋 同心圓電極 運(yùn)算放大器 開關(guān)電容濾波器

【摘要】：對(duì)于癱瘓病人的治療和康復(fù)一直以來都是醫(yī)學(xué)界的難題,現(xiàn)有的醫(yī)學(xué)治療方法治療效率低,治療成本偏高,且康復(fù)效果因人而異。另一方面隨著信息技術(shù)的高速發(fā)展,信息學(xué)與生物學(xué)產(chǎn)生了學(xué)科交叉,利用微電子的方法為受損的神經(jīng)建立輔助信號(hào)通路成為了一種可能。理論上,通過上述方法可以實(shí)現(xiàn)受損神經(jīng)的功能再生,從而為治療癱瘓?zhí)峁┝艘粭l新的途徑。本文首先對(duì)微電子肌電信號(hào)橋接電路的相關(guān)理論做研究分析。對(duì)比課題組之前實(shí)驗(yàn)結(jié)果,提出了用同心圓電極作為激勵(lì)電極的重建方法,并在此基礎(chǔ)上確定了電路結(jié)構(gòu)以及設(shè)計(jì)指標(biāo)。采用CSMC0.5μm CMOS工藝設(shè)計(jì)了微電子肌電橋關(guān)鍵電路,芯片電路由肌電信號(hào)探測(cè)電路、直流偏移補(bǔ)償電路、帶通濾波電路和信號(hào)放大電路四個(gè)部分組成。并根據(jù)指標(biāo)需要設(shè)計(jì)了兩種專門的運(yùn)算放大器：折疊式共源共柵的兩級(jí)運(yùn)算放大器和恒定跨導(dǎo)滿擺幅輸入輸出的兩級(jí)運(yùn)算放大器。后仿真結(jié)果顯示,折疊式共源共柵兩級(jí)運(yùn)算放大器具有104.6dB的高開環(huán)增益,86.4。的高相位裕度,7.9MHz的帶寬,以及7.75×10-16 V2/Hz@1kHz低輸入噪聲。恒定跨導(dǎo)滿擺幅輸入輸出兩級(jí)運(yùn)算放大器輸入具有接近電源電壓的輸入輸出電平以及4.9%的低跨導(dǎo)誤差,滿足系統(tǒng)電路對(duì)運(yùn)算放大器的專門需求。芯片內(nèi)濾波器通過調(diào)節(jié)外接電容容抗的方式來調(diào)節(jié)截止頻率,芯片面積1150μm×950gm,工作在±2.5V的電源電壓下,功耗為4.57mW,外接33nF電容時(shí),系統(tǒng)工作頻段為95.98Hz-6.26kHz。在該工作頻段內(nèi)能正常放大信號(hào)。上述結(jié)構(gòu)電路的下截止頻率是95.98Hz,而肌電信號(hào)在95.98Hz的頻率以下也存在。針對(duì)它們頻段不吻合的情況,對(duì)上述電路進(jìn)行了改進(jìn)。引入開關(guān)電容有源濾波器的電路結(jié)構(gòu)。優(yōu)化后的電路不但降低了電路系統(tǒng)的下截止頻率,并且由于只需要調(diào)節(jié)輸入采樣信號(hào)的頻率就可以調(diào)節(jié)電路的工作頻率,引入的片外干擾更小,片內(nèi)集成度更高,更加符合生物實(shí)驗(yàn)和臨床要求。系統(tǒng)電路工作在±2.5V電源電壓下,芯片面積1150μm×1000μm,工作頻率為1.15Hz-2.65kHz,與肌電信號(hào)頻段相符,直流功耗5.33mW,實(shí)現(xiàn)了肌電信號(hào)橋接并放大的功能。
[Abstract]:The treatment and rehabilitation of paralyzed patients has always been a difficult problem in the medical field. The existing medical treatment methods have low efficiency and high treatment cost. On the other hand, with the rapid development of information technology, informatics and biology have interdiscipline. It is possible to establish an auxiliary signal pathway for the injured nerve by using microelectronic method. Theoretically, the injured nerve can be regenerated by the above methods. This provides a new way for the treatment of paralysis. Firstly, this paper studies and analyzes the theory of the bridge circuit of microelectronic EMG signal, and compares the experimental results before the research group. A reconstruction method using concentric circular electrode as excitation electrode is proposed. On this basis, the circuit structure and design index are determined. The key circuit of microelectronic myoelectric bridge is designed by CSMC0.5 渭 m CMOS technology, and the chip circuit is detected by EMG signal. DC offset compensation circuit. Four parts are composed of band-pass filter circuit and signal amplifying circuit. Two special operational amplifiers are designed according to the requirements of the index. The two-stage operational amplifier of the foldable common-gate and the two-stage operational amplifier with constant transconductance full swing input and output. The post-simulation results show. The foldable common-grid two-stage operational amplifier has a high open-loop gain of 104.6dB and a high phase margin of 7.9MHz. And 7.75 脳 10-16. V2 / Hz@ 1kHz low input noise. Constant transconductance full swing input and output two stage operational amplifier input and output level close to the supply voltage and low transconductance error of 4.9%. The on-chip filter adjusts the cutoff frequency by adjusting the capacitive reactance of the external capacitor. The chip area is 1150 渭 m 脳 950gm. When the power consumption is 4.57mW and the external capacitor is 33nF, the power consumption is 4.57mW at 鹵2.5V power supply voltage. The operating frequency range of the system is 95.98Hz-6.26kHz. The signal can be amplified normally in the working band. The lower cut-off frequency of the circuit is 95.98Hz. EMG signals also exist at the frequency of 95.98 Hz. The circuit structure of switched capacitor active filter is introduced. The optimized circuit not only reduces the lower cutoff frequency of the circuit system. Since only the frequency of the input sampling signal can be adjusted, the out-of-chip interference is smaller and the in-chip integration is higher. The system circuit works at 鹵2.5V power supply voltage, the chip area is 1150 渭 m 脳 1000 渭 m, and the working frequency is 1.15Hz-2.65kHz. In accordance with the frequency band of EMG signal, the DC power consumption is 5.33mW. the bridge and amplification function of EMG signal is realized.
【學(xué)位授予單位】：東南大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2015
【分類號(hào)】：R496;TN402

【參考文獻(xiàn)】

相關(guān)期刊論文 前10條

1 ;我國(guó)腦卒中發(fā)病人數(shù)增長(zhǎng)驚人[J];家庭醫(yī)藥(快樂養(yǎng)生);2013年12期

2 張宋誠(chéng);司峻峰;黃曉林;肇瑩;劉紅星;;高通濾波器積分反饋實(shí)現(xiàn)方式的拓展[J];儀器儀表學(xué)報(bào);2013年07期

3 鄭萍;盛夏;;肌電誘發(fā)神經(jīng)肌肉電刺激對(duì)腦卒中偏癱患者上肢運(yùn)動(dòng)功能的療效[J];中國(guó)康復(fù)理論與實(shí)踐;2012年01期

4 楊彥玲;師養(yǎng)榮;;脊髓損傷治療的研究進(jìn)展[J];中國(guó)臨床神經(jīng)外科雜志;2011年10期

5 朱兵;黃龍祥;楊金生;張麗;王瑩瑩;趙京生;吳中朝;崗衛(wèi)娟;;“中醫(yī)針灸”申報(bào)人類非物質(zhì)文化遺產(chǎn)代表作名錄文本解析[J];中國(guó)針灸;2011年03期

6 范濤;彭杰;張崢;袁國(guó)順;黃強(qiáng);;帶通開關(guān)電容濾波器的設(shè)計(jì)和仿真方法[J];微電子學(xué)與計(jì)算機(jī);2009年12期

7 朱穎佳;劉力源;李冬梅;;一種獨(dú)立調(diào)節(jié)兩相脈寬的不交疊時(shí)鐘產(chǎn)生電路[J];半導(dǎo)體技術(shù);2009年10期

8 崔利平;;儀表放大器電路設(shè)計(jì)[J];現(xiàn)代電子技術(shù);2009年11期

9 鄧?guó)P君;楊迎暴;徐江平;;脊髓損傷治療藥物的研究進(jìn)展[J];中國(guó)藥理學(xué)通報(bào);2009年02期

10 甄志芳;趙毅;張福海;;超大時(shí)間常數(shù)開關(guān)電容積分器設(shè)計(jì)[J];南開大學(xué)學(xué)報(bào)(自然科學(xué)版);2008年03期

相關(guān)博士學(xué)位論文 前2條

1 雷亞玲;中醫(yī)藥治療急性缺血性腦卒中（AIS）的文獻(xiàn)計(jì)量分析及臨床研究[D];廣州中醫(yī)藥大學(xué);2014年

2 陳熙;生物學(xué)哲學(xué)中的機(jī)制研究[D];浙江大學(xué);2011年

相關(guān)碩士學(xué)位論文 前2條

1 梁凱;生物醫(yī)學(xué)信號(hào)CMOS模擬前端芯片設(shè)計(jì)與研究[D];華南理工大學(xué);2012年

2 周海龍;微傳感器中開關(guān)電容式濾波器設(shè)計(jì)[D];哈爾濱工業(yè)大學(xué);2010年

，

本文編號(hào)：1377460